Success Metrics

Clinical Success Rate
85.7%

Based on 18 completed trials

Completion Rate
86%(18/21)
Active Trials
4(12%)
Results Posted
22%(4 trials)
Terminated
3(9%)

Phase Distribution

Ph phase_1
6
18%
Ph early_phase_1
1
3%
Ph not_applicable
11
33%
Ph phase_2
7
21%
Ph phase_3
4
12%

Phase Distribution

7

Early Stage

7

Mid Stage

4

Late Stage

Phase Distribution29 total trials
Early Phase 1First-in-human
1(3.4%)
Phase 1Safety & dosage
6(20.7%)
Phase 2Efficacy & side effects
7(24.1%)
Phase 3Large-scale testing
4(13.8%)
N/ANon-phased studies
11(37.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

75.0%

18 of 24 finished

Non-Completion Rate

25.0%

6 ended early

Currently Active

4

trials recruiting

Total Trials

33

all time

Status Distribution
Active(5)
Completed(18)
Terminated(6)
Other(4)

Detailed Status

Completed18
Recruiting4
unknown4
Terminated3
Withdrawn3
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
33
Active
4
Success Rate
85.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (3.4%)
Phase 16 (20.7%)
Phase 27 (24.1%)
Phase 34 (13.8%)
N/A11 (37.9%)

Trials by Status

terminated39%
withdrawn39%
recruiting412%
not_yet_recruiting13%
completed1855%
unknown412%

Recent Activity

4 active trials
Showing 5 of 33
recruitingnot_applicable

Systemic Hypothermia in Acute Cervical Spinal Cord Injury

NCT02991690
recruitingphase_2

Trial of Therapeutic Hypothermia in Patients With ARDS

NCT04545424
completednot_applicable

Efficacy of IV Fluid Warmer for the Prevention of Hypothermia

NCT07192224
completednot_applicable

Benefit of Hypothermia in OHCA Complicating AMI

NCT06141252
recruitingphase_3

Combination of Hypothermia and Thrombectomy in Acute Stroke

NCT06301412
View all 33 trials

Clinical Trials (33)

Showing 20 of 33 trialsScroll for more
NCT02991690Not Applicable

Systemic Hypothermia in Acute Cervical Spinal Cord Injury

Recruiting
NCT04545424Phase 2

Trial of Therapeutic Hypothermia in Patients With ARDS

Recruiting
NCT07192224Not Applicable

Efficacy of IV Fluid Warmer for the Prevention of Hypothermia

Completed
NCT06141252Not Applicable

Benefit of Hypothermia in OHCA Complicating AMI

Completed
NCT06301412Phase 3

Combination of Hypothermia and Thrombectomy in Acute Stroke

Recruiting
NCT06665386

Prognostic Biomarkers for Selective Intra-Arterial Cooling Infusion Combined with Endovascular Thrombectomy in Acute Ischemic Stroke Based on Proteomics and Metabolomics.

Recruiting
NCT01793129Not Applicable

Preemie Hypothermia for Neonatal Encephalopathy

Completed
NCT05908630

Accidental Hypothermia in Drowning-related OHCA

Completed
NCT02551003Phase 1

Neuroprotective Effect of Autologous Cord Blood Combined With Therapeutic Hypothermia Following Neonatal Encephalopathy

Withdrawn
NCT06109376Not Applicable

Role of Hypothermia in Endovascular Stroke Thrombectomy

Not Yet Recruiting
NCT05986994

Identification of a Pool of miRNA to Improve Early Management of Perinatal Asphyxia and Hypoxic Ischemic Encephalopathy

Unknown
NCT02244034

Incidence and Risk Factors of Postoperative Hypothermia in Cardiac Surgery

Completed
NCT00754481Phase 2

Hypothermia for Cardiac Arrest in Paediatrics

Completed
NCT03376854Phase 2

Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS

Withdrawn
NCT00614744Not Applicable

Late Hypothermia for Hypoxic-Ischemic Encephalopathy

Completed
NCT01833312Phase 3

Cooling Plus Best Medical Treatment Versus Best Medical Treatment Alone for Acute Ischaemic Stroke

Terminated
NCT00987688Not Applicable

The Prophylactic Hypothermia Trial to Lessen Traumatic Brain Injury

Completed
NCT03299582Not Applicable

PREventing CHemotherapy Induced Neuropathy (PreChIN)

Completed
NCT02826941Phase 2

Moderate Hypothermia in Neonatal Hypoxic Ischemic Encephalopathy

Completed
NCT01607151Phase 1

Safety and Feasibility Study of Targeted Temperature Management After ICH

Unknown

Drug Details

Intervention Type
OTHER
Total Trials
33