Registry-listed formulations

hydroquinone · mesh:C031927

Each study is counted once in the molecule profile. Registry products remain separate. Naming an ingredient does not establish that products are interchangeable or what participants received.

15 source entries across 15 studies. This list may not include all unresolved or historical entries.

  • hydroquinone creamRegistry intervention

    Linked study entry; product equivalence not established

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  • 4% Hydroquinone Topical CreamRegistry intervention

    Linked study entry; product equivalence not established

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  • 4% hydroquinone creamRegistry intervention

    Linked study entry; product equivalence not established

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  • 4% hydroquinoneRegistry intervention

    Linked study entry; product equivalence not established

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  • Hydroquinone 4% CreamRegistry intervention

    Linked study entry; product equivalence not established

    Named ingredient; exact form unconfirmed. This mention does not add to the molecule trial count.

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  • Hydroquinone 4% CreamRegistry intervention

    Linked study entry; product equivalence not established

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  • topical 2% hydroquinoneRegistry intervention

    Linked study entry; product equivalence not established

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  • Hydroquinone TopicalRegistry intervention

    Linked study entry; product equivalence not established

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  • 2% HydroquinoneRegistry intervention

    Linked study entry; product equivalence not established

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  • Hydroquinone CreamRegistry intervention

    Linked study entry; product equivalence not established

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  • Active Comparator: Group HQ: Hydroquinone 4%Registry intervention

    Linked study entry; product equivalence not established

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  • Hydroquinone creamRegistry intervention

    Linked study entry; product equivalence not established

    View study and source
  • 2% hydroquinone creamRegistry intervention

    Linked study entry; product equivalence not established

    View study and source
  • Topical 4% hydroquinone creamRegistry intervention

    Linked study entry; product equivalence not established

    View study and source
  • Hydroquinone 4% CreamRegistry intervention

    Linked study entry; product equivalence not established

    View study and source

Success Metrics

Clinical Success Rate
100.0%

Based on 13 completed trials

Completion Rate
100%(13/13)
Active Trials
1(5%)
Results Posted
8%(1 trials)

Phase Distribution

Not Applicable
7
37%
Phase 2
4
21%
Phase 3
3
16%
Phase 4
5
26%

Phase Distribution

0

Early Stage

4

Mid Stage

8

Late Stage

Phase Distribution19 total trials
Phase 2Efficacy & side effects
4(21.1%)
Phase 3Large-scale testing
3(15.8%)
Phase 4Post-market surveillance
5(26.3%)
N/ANon-phased studies
7(36.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

100.0%

13 of 13 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

1

trials recruiting

Total Trials

19

all time

Status Distribution
Active(2)
Completed(13)
Other(4)

Detailed Status

Completed13
unknown4
Recruiting1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
19
Active
1
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 24 (21.1%)
Phase 33 (15.8%)
Phase 45 (26.3%)
N/A7 (36.8%)

Trials by Status

unknown421%
recruiting15%
completed1368%
not_yet_recruiting15%

Recent Activity

1 active trials
Showing 5 of 19
recruitingphase_4

Prospective Evaluation of Topical Almond Oil vs Hydroquinone

NCT04875715
completedphase_4

Comparison of Efficacy of Topical Westerhoff Formula Cream Vs Topical 4% Hydroquinone for the Treatment of Melasma

NCT07508098
completednot_applicable

Azelaic Acid 20% vs Hydroquinone 4% in Epidermal Melasma

NCT07327983
not_yet_recruitingnot_applicable

Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES

NCT07121439
completedphase_2

Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study

NCT06957834
View all 19 trials

Clinical Trials (19)

Showing 19 of 19 trials
NCT04875715Phase 4

Prospective Evaluation of Topical Almond Oil vs Hydroquinone

Recruiting
NCT07508098Phase 4

Comparison of Efficacy of Topical Westerhoff Formula Cream Vs Topical 4% Hydroquinone for the Treatment of Melasma

Completed
NCT07327983Not Applicable

Azelaic Acid 20% vs Hydroquinone 4% in Epidermal Melasma

Completed
NCT07121439Not Applicable

Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES

Not Yet Recruiting
NCT06957834Phase 2

Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study

Completed
NCT06787846Not Applicable

EFFICACY and TOLERABILITY of TESTED FORMULA VS. HYDROQUINONE 4% in the TREATMENT of FACIAL MELASMA

Completed
NCT05511948Phase 2

Randomized and Open Label Study for Safety and Efficacy of DBI-102 vs. Vehicle vs. Hydroquinone on Skin Pigmentation and Lentigos

Completed
NCT05013801Not Applicable

A Clinical Study to Evaluate the Effect of Facial Serum Q69 in Moderating the Appearance of Mild to Moderate Melasma

Completed
NCT04597203Not Applicable

Efficacy and Safety of Using Combination of 755-nm Picosecond Alexandrite Laser and 2% Hydroquinone Compared With 2% Hydroquinone Alone for the Treatment of Melasma: a Randomized Split-face Controlled Trial

Unknown
NCT04345094Not Applicable

Evaluation of Hexyresorcinol vs Hydroquinone for Photoaging

Completed
NCT03982849Phase 2

Comparison of Topical Silymarin With Hydroquinone in the Treatment of Melasma

Completed
NCT02095990Phase 3

Efficacy and Safety of a 4% Hydroquinone Cream for the Treatment of Melasma

Completed
NCT02977507Not Applicable

Split-face Study Comparing the Cosmetic Efficacy and Tolerability of Two Topical Products in Participants With Moderate Facial Melasma

Completed
NCT03751163Phase 3

Oral Tranexamic Acid and Topical Hydroquinone in the Treatment of Melasma

Completed
NCT03585179Phase 3

Oral and Topical Tranexamic Acid for the Treatment of Melasma

Unknown
NCT03049059Phase 2

A Comparative Study for Efficacy and Safety Between 4% Hydroquinone Cream With or Without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma

Completed
NCT02138539Phase 4

Evaluation of an Herbal-Based De-Pigmenting System

Completed
NCT01661556Phase 4

Clinical Trial of Hydroquinone Versus Miconazol in Melasma

Unknown
NCT00927771Phase 4

Azelaic Acid Versus Hydroquinone in Melasma

Unknown

All 19 trials loaded

Drug Details

Intervention Type
Varies by study
Molecule Type
Small molecule
Total Trials
19

External References

ChEMBL
CHEMBL537

Names & Codes

Trade Names

ArtraEldopaqueEldoquinEsotericaHidroquilaudeHidroquinHidroquinona IsdinLicostrataLustraMelanasaMelanexMelpaqueMelquinNeostrata HQPhiaquinSolaquinUltraquin

ATC Classification

D11AX11

Research Codes

CHEBI:17594CHEMBL537NCI-C55834NSC-9247