Success Metrics

Clinical Success Rate
80.0%

Based on 24 completed trials

Completion Rate
80%(24/30)
Active Trials
6(16%)
Results Posted
38%(9 trials)
Terminated
6(16%)

Phase Distribution

Ph phase_1
9
24%
Ph phase_2
24
63%
Ph phase_3
5
13%

Phase Distribution

9

Early Stage

24

Mid Stage

5

Late Stage

Phase Distribution38 total trials
Phase 1Safety & dosage
9(23.7%)
Phase 2Efficacy & side effects
24(63.2%)
Phase 3Large-scale testing
5(13.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

80.0%

24 of 30 finished

Non-Completion Rate

20.0%

6 ended early

Currently Active

6

trials recruiting

Total Trials

38

all time

Status Distribution
Active(6)
Completed(24)
Terminated(6)
Other(2)

Detailed Status

Completed24
Terminated6
Recruiting3
Active, not recruiting3
unknown2

Development Timeline

Analytics

Development Status

Total Trials
38
Active
6
Success Rate
80.0%
Most Advanced
Phase 3

Trials by Phase

Phase 19 (23.7%)
Phase 224 (63.2%)
Phase 35 (13.2%)

Trials by Status

completed2463%
terminated616%
recruiting38%
unknown25%
active_not_recruiting38%

Recent Activity

Clinical Trials (38)

Showing 20 of 38 trialsScroll for more
NCT05863195Phase 3

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Recruiting
NCT05286814Phase 2

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Recruiting
NCT06313203Phase 2

HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT)

Recruiting
NCT00492999Phase 2

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Active Not Recruiting
NCT04251715Phase 2

mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma

Active Not Recruiting
NCT00059930Phase 1

Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer

Completed
NCT00410956Phase 2

Floxuridine and Dexamethasone as a Hepatic Arterial Infusion and Bevacizumab in Treating Patients With Primary Liver Cancer That Cannot be Removed by Surgery

Completed
NCT04898504Phase 2

HAI-Floxuridine, or Liver-Tx, Combined With 2nd Line Chemotherapy Versus 2nd Line Chemotherapy Alone for Patients With Colorectal Liver Metastases and Heavy Tumour Burden.

Active Not Recruiting
NCT00019760Phase 2

Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver

Completed
NCT00587067Phase 2

A Phase II Study of Continuous Hepatic Arterial Infusion With Floxuridine (FUDR) and Dexamethasone (DEX) in Patients With Unresectable Primary Hepatic Malignancy

Completed
NCT03678428Phase 3

FUDR/Oxaliplatin HAI Plus Irinotecan vs. FOLFOXIRI Chemotherapy in Treating Initially Unresectable CRCLM

Terminated
NCT03493061Phase 2

A Study of Systemic Chemotherapy With CPT-11 Plus HAI (FUDR+L-OHP) in Patients With Initially Unresectable CRCLM

Completed
NCT01525069Phase 1

Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma

Terminated
NCT04552093Phase 2

Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT)

Unknown
NCT01938729Phase 1

Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Gemcitabine as Adjuvant Treatment After Resection of Intrahepatic Cholangiocarcinoma

Completed
NCT01749397Phase 1

Veliparib and Floxuridine in Treating Patients With Metastatic Epithelial Ovarian, Primary Peritoneal Cavity, or Fallopian Tube Cancer

Completed
NCT00645710Phase 1

Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery

Completed
NCT03876574Phase 1

Hepatic Artery Infusion Pump for NPC Liver Metastases

Completed
NCT00004142Phase 2

Radiofrequency Ablation Followed By Hepatic Artery Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Completed
NCT00848783Phase 2

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
38