Success Metrics

Clinical Success Rate
84.8%

Based on 106 completed trials

Completion Rate
85%(106/125)
Active Trials
33(17%)
Results Posted
73%(77 trials)
Terminated
19(10%)

Phase Distribution

Ph phase_4
7
4%
Ph phase_1
28
15%
Ph phase_2
84
44%
Ph phase_3
54
29%
Ph not_applicable
8
4%

Phase Distribution

28

Early Stage

84

Mid Stage

61

Late Stage

Phase Distribution181 total trials
Phase 1Safety & dosage
28(15.5%)
Phase 2Efficacy & side effects
84(46.4%)
Phase 3Large-scale testing
54(29.8%)
Phase 4Post-market surveillance
7(3.9%)
N/ANon-phased studies
8(4.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.3%

106 of 132 finished

Non-Completion Rate

19.7%

26 ended early

Currently Active

33

trials recruiting

Total Trials

189

all time

Status Distribution
Active(35)
Completed(106)
Terminated(26)
Other(22)

Detailed Status

Completed106
unknown21
Terminated19
Recruiting18
Active, not recruiting15
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
189
Active
33
Success Rate
84.8%
Most Advanced
Phase 4

Trials by Phase

Phase 128 (15.5%)
Phase 284 (46.4%)
Phase 354 (29.8%)
Phase 47 (3.9%)
N/A8 (4.4%)

Trials by Status

not_yet_recruiting21%
recruiting1810%
unknown2111%
withdrawn74%
suspended11%
terminated1910%
active_not_recruiting158%
completed10656%

Recent Activity

Clinical Trials (189)

Showing 20 of 189 trialsScroll for more
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT01272037Phase 3

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Active Not Recruiting
NCT02115282Phase 3

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

Active Not Recruiting
NCT06380751Phase 3

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Recruiting
NCT07174336Phase 3

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Recruiting
NCT06169124Phase 2

Study to Test the Drug Darolutamide Along With the Drugs Leuprolide Acetate and Exemestane in Patients With Recurrent Ovarian Granulosa Cell Tumors

Active Not Recruiting
NCT02476786Phase 2

Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score

Recruiting
NCT04975308Phase 3

A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

Active Not Recruiting
NCT07391774Phase 3

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Recruiting
NCT06075953Phase 2

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Recruiting
NCT05774951Phase 3

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Recruiting
NCT06979596Phase 2

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Recruiting
NCT04572295Phase 1

A Study of E7090 as Monotherapy and in Combination With Other Anticancer Agents in Participants With Estrogen Receptor Positive (ER+) and Human Epidermal Growth Receptor 2 Negative (HER2-) Recurrent/Metastatic Breast Cancer

Completed
NCT05827081Phase 3

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

Recruiting
NCT05467891Phase 2

Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

Recruiting
NCT06428396Phase 2

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Active Not Recruiting
NCT06492616Phase 3

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Recruiting
NCT05768139Phase 1

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Recruiting
NCT06001762Phase 2

TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer

Active Not Recruiting
NCT06671912Phase 3

Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial

Suspended

Drug Details

Intervention Type
DRUG
Total Trials
189