Success Metrics

Clinical Success Rate
84.6%

Based on 104 completed trials

Completion Rate
85%(104/123)
Active Trials
35(19%)
Results Posted
73%(76 trials)
Terminated
19(10%)

Phase Distribution

Ph phase_1
28
15%
Ph phase_3
54
29%
Ph not_applicable
8
4%
Ph phase_2
84
44%
Ph phase_4
7
4%

Phase Distribution

28

Early Stage

84

Mid Stage

61

Late Stage

Phase Distribution181 total trials
Phase 1Safety & dosage
28(15.5%)
Phase 2Efficacy & side effects
84(46.4%)
Phase 3Large-scale testing
54(29.8%)
Phase 4Post-market surveillance
7(3.9%)
N/ANon-phased studies
8(4.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.0%

104 of 130 finished

Non-Completion Rate

20.0%

26 ended early

Currently Active

35

trials recruiting

Total Trials

189

all time

Status Distribution
Active(37)
Completed(104)
Terminated(26)
Other(22)

Detailed Status

Completed104
unknown21
Recruiting19
Terminated19
Active, not recruiting16
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
189
Active
35
Success Rate
84.6%
Most Advanced
Phase 4

Trials by Phase

Phase 128 (15.5%)
Phase 284 (46.4%)
Phase 354 (29.8%)
Phase 47 (3.9%)
N/A8 (4.4%)

Trials by Status

recruiting1910%
completed10455%
active_not_recruiting168%
terminated1910%
not_yet_recruiting21%
suspended11%
unknown2111%
withdrawn74%

Recent Activity

Clinical Trials (189)

Showing 20 of 189 trialsScroll for more
NCT07391774Phase 3

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Recruiting
NCT01272037Phase 3

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Active Not Recruiting
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT05827081Phase 3

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

Recruiting
NCT06671912Phase 3

Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial

Suspended
NCT05768139Phase 1

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Recruiting
NCT07174336Phase 3

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Recruiting
NCT02115282Phase 3

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

Active Not Recruiting
NCT05952557Phase 3

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Recruiting
NCT06492616Phase 3

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Recruiting
NCT06075953Phase 2

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Recruiting
NCT06428396Phase 2

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Recruiting
NCT06380751Phase 3

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Recruiting
NCT06169124Phase 2

Study to Test the Drug Darolutamide Along With the Drugs Leuprolide Acetate and Exemestane in Patients With Recurrent Ovarian Granulosa Cell Tumors

Active Not Recruiting
NCT06979596Phase 2

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Recruiting
NCT05774951Phase 3

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Recruiting
NCT07062965Phase 3

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

Recruiting
NCT03179904Phase 2

TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer

Active Not Recruiting
NCT05306340Phase 3

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

Active Not Recruiting
NCT06630325Phase 2

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
189