Success Metrics

Clinical Success Rate
78.2%

Based on 283 completed trials

Completion Rate
78%(283/362)
Active Trials
64(13%)
Results Posted
75%(211 trials)
Terminated
79(16%)

Phase Distribution

Ph not_applicable
15
3%
Ph phase_2
199
39%
Ph phase_4
64
13%
Ph phase_1
142
28%
Ph early_phase_1
7
1%
Ph phase_3
66
13%

Phase Distribution

149

Early Stage

199

Mid Stage

130

Late Stage

Phase Distribution493 total trials
Early Phase 1First-in-human
7(1.4%)
Phase 1Safety & dosage
142(28.8%)
Phase 2Efficacy & side effects
199(40.4%)
Phase 3Large-scale testing
66(13.4%)
Phase 4Post-market surveillance
64(13.0%)
N/ANon-phased studies
15(3.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.7%

283 of 374 finished

Non-Completion Rate

24.3%

91 ended early

Currently Active

64

trials recruiting

Total Trials

504

all time

Status Distribution
Active(75)
Completed(283)
Terminated(91)
Other(55)

Detailed Status

Completed283
Terminated79
unknown54
Recruiting33
Active, not recruiting31
Withdrawn12

Development Timeline

Analytics

Development Status

Total Trials
504
Active
64
Success Rate
78.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (1.4%)
Phase 1142 (28.8%)
Phase 2199 (40.4%)
Phase 366 (13.4%)
Phase 464 (13.0%)
N/A15 (3.0%)

Trials by Status

suspended10%
active_not_recruiting316%
completed28356%
not_yet_recruiting102%
recruiting337%
unknown5411%
enrolling_by_invitation10%
withdrawn122%
terminated7916%

Recent Activity

Clinical Trials (504)

Showing 20 of 504 trialsScroll for more
NCT05773274Phase 2

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

Recruiting
NCT06943755Phase 2

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

Recruiting
NCT02711826Phase 1

Treg Therapy in Subclinical Inflammation in Kidney Transplantation

Completed
NCT04066114Phase 1

Treg Modulation With CD28 and IL-6 Receptor Antagonists

Completed
NCT05188118Early Phase 1

Rapid Sequencing of Approved Therapies in Patients With Metastatic or Unresectable Clear Cell Renal Cell Carcinoma

Completed
NCT03950609Phase 2

Lenvatinib and Everolimus in Treating Patients With Advanced, Unresectable Carcinoid Tumors

Active Not Recruiting
NCT04665739Phase 2

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

Recruiting
NCT06280950Phase 2

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

Recruiting
NCT05252585Phase 4

A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)

Active Not Recruiting
NCT03577431Phase 1

Liver Transplantation With Tregs at MGH

Completed
NCT05508906Phase 1

Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

Active Not Recruiting
NCT05012371Phase 2

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

Active Not Recruiting
NCT02397083Phase 2

Levonorgestrel-Releasing Intrauterine System With or Without Everolimus in Treating Patients With Atypical Hyperplasia or Stage IA Grade 1 Endometrial Cancer

Active Not Recruiting
NCT04802759Phase 1

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Recruiting
NCT01582191Phase 1

Vandetanib and Everolimus in Treating Patients With Advanced or Metastatic Cancer

Completed
NCT06428396Phase 2

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Active Not Recruiting
NCT06382948Phase 3

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

Recruiting
NCT02962414Phase 3

Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment

Active Not Recruiting
NCT03740334Phase 1

Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

Active Not Recruiting
NCT06105632Phase 2

A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
504