Success Metrics

Clinical Success Rate
78.1%

Based on 278 completed trials

Completion Rate
78%(278/356)
Active Trials
66(13%)
Results Posted
74%(207 trials)
Terminated
78(16%)

Phase Distribution

Ph early_phase_1
7
1%
Ph phase_3
66
13%
Ph not_applicable
15
3%
Ph phase_1
142
28%
Ph phase_4
64
13%
Ph phase_2
197
39%

Phase Distribution

149

Early Stage

197

Mid Stage

130

Late Stage

Phase Distribution491 total trials
Early Phase 1First-in-human
7(1.4%)
Phase 1Safety & dosage
142(28.9%)
Phase 2Efficacy & side effects
197(40.1%)
Phase 3Large-scale testing
66(13.4%)
Phase 4Post-market surveillance
64(13.0%)
N/ANon-phased studies
15(3.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.5%

278 of 368 finished

Non-Completion Rate

24.5%

90 ended early

Currently Active

66

trials recruiting

Total Trials

502

all time

Status Distribution
Active(76)
Completed(278)
Terminated(90)
Other(58)

Detailed Status

Completed278
Terminated78
unknown56
Recruiting36
Active, not recruiting30
Withdrawn12

Development Timeline

Analytics

Development Status

Total Trials
502
Active
66
Success Rate
78.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (1.4%)
Phase 1142 (28.9%)
Phase 2197 (40.1%)
Phase 366 (13.4%)
Phase 464 (13.0%)
N/A15 (3.1%)

Trials by Status

recruiting367%
suspended20%
completed27855%
terminated7816%
enrolling_by_invitation10%
unknown5611%
withdrawn122%
not_yet_recruiting92%
active_not_recruiting306%

Recent Activity

Clinical Trials (502)

Showing 20 of 502 trialsScroll for more
NCT05773274Phase 2

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

Recruiting
NCT07062965Phase 3

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

Recruiting
NCT03577431Phase 1

Liver Transplantation With Tregs at MGH

Active Not Recruiting
NCT04665739Phase 2

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

Recruiting
NCT06280950Phase 2

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

Recruiting
NCT07405164Phase 3

Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

Recruiting
NCT05306340Phase 3

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

Active Not Recruiting
NCT06428396Phase 2

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Recruiting
NCT07165886Phase 2

Sirolimus for Injection (Albumin Bound) Combined With Octreotide Long-acting Injection in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors

Recruiting
NCT05843253Phase 2

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Recruiting
NCT06943755Phase 2

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

Recruiting
NCT04802759Phase 1

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Recruiting
NCT04485559Phase 1

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

Suspended
NCT02962414Phase 3

Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment

Active Not Recruiting
NCT05252585Phase 4

A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)

Active Not Recruiting
NCT05477576Phase 3

Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

Recruiting
NCT05573126Phase 1

Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

Recruiting
NCT03950609Phase 2

Lenvatinib and Everolimus in Treating Patients With Advanced, Unresectable Carcinoid Tumors

Active Not Recruiting
NCT07477548Phase 2

A Study to Evaluate the Efficacy and Safety of Everolimus in Patients With Teratment-refractory Vascular Anomalies

Not Yet Recruiting
NCT06382948Phase 3

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
502