Success Metrics

Clinical Success Rate
78.1%

Based on 281 completed trials

Completion Rate
78%(281/360)
Active Trials
64(13%)
Results Posted
75%(210 trials)
Terminated
79(16%)

Phase Distribution

Ph phase_2
199
39%
Ph phase_3
66
13%
Ph early_phase_1
7
1%
Ph phase_1
142
28%
Ph not_applicable
15
3%
Ph phase_4
64
13%

Phase Distribution

149

Early Stage

199

Mid Stage

130

Late Stage

Phase Distribution493 total trials
Early Phase 1First-in-human
7(1.4%)
Phase 1Safety & dosage
142(28.8%)
Phase 2Efficacy & side effects
199(40.4%)
Phase 3Large-scale testing
66(13.4%)
Phase 4Post-market surveillance
64(13.0%)
N/ANon-phased studies
15(3.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.5%

281 of 372 finished

Non-Completion Rate

24.5%

91 ended early

Currently Active

64

trials recruiting

Total Trials

504

all time

Status Distribution
Active(76)
Completed(281)
Terminated(91)
Other(56)

Detailed Status

Completed281
Terminated79
unknown55
Recruiting33
Active, not recruiting31
Withdrawn12

Development Timeline

Analytics

Development Status

Total Trials
504
Active
64
Success Rate
78.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (1.4%)
Phase 1142 (28.8%)
Phase 2199 (40.4%)
Phase 366 (13.4%)
Phase 464 (13.0%)
N/A15 (3.0%)

Trials by Status

not_yet_recruiting112%
withdrawn122%
enrolling_by_invitation10%
recruiting337%
suspended10%
terminated7916%
completed28156%
unknown5511%
active_not_recruiting316%

Recent Activity

Clinical Trials (504)

Showing 20 of 504 trialsScroll for more
NCT03049189Phase 3

Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients

Active Not Recruiting
NCT06943755Phase 2

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

Recruiting
NCT05773274Phase 2

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

Recruiting
NCT04802759Phase 1

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Recruiting
NCT01805271Phase 3

Safety Study of Adding Everolimus to Adjuvant Hormone Therapy in Women With High Risk of Relapse, ER+ and HER2- Primary Breast Cancer, Free of Disease After Receiving at Least One Year of Adjuvant Hormone Therapy

Active Not Recruiting
NCT07739914Phase 3

Everolimus bAsed caLcineurin inhibiTor frEe immunosuppRession oNe Year AfTer lIver transplantatiON (ALTERNATION)

Not Yet Recruiting
NCT03386539Phase 3

Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score

Completed
NCT04665739Phase 2

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

Recruiting
NCT01797523Phase 2

A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma

Completed
NCT05188118Early Phase 1

Rapid Sequencing of Approved Therapies in Patients With Metastatic or Unresectable Clear Cell Renal Cell Carcinoma

Completed
NCT02328963Phase 4

Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporine Versus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A

Completed
NCT06280950Phase 2

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

Recruiting
NCT03065387Phase 1

Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

Terminated
NCT01087554Phase 1

Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced Cancer

Active Not Recruiting
NCT01217931Phase 2

Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START Trial

Active Not Recruiting
NCT06428396Phase 2

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Active Not Recruiting
NCT02813135Phase 1

European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors

Recruiting
NCT07318324Phase 1

Phase Ib Study of Avutometinib, Defactinib, and Everolimus in RAS Pathway Mutant Endometrial Cancer

Recruiting
NCT03032406Phase 2

CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine, EVErolimus or the Combination for Prevention of Recurrent Breast Cancer

Active Not Recruiting
NCT06126588Phase 2

Combination of Everolimus and 177Lu-DOTATATE in the Treatment of Grades 2 and 3 Refractory Meningioma: a Phase IIb Clinical Trial

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
504