Success Metrics

Clinical Success Rate
81.1%

Based on 30 completed trials

Completion Rate
81%(30/37)
Active Trials
3(5%)
Results Posted
37%(11 trials)
Terminated
7(11%)

Phase Distribution

Ph not_applicable
13
21%
Ph phase_3
5
8%
Ph phase_2
16
26%
Ph phase_1
4
7%
Ph phase_4
20
33%

Phase Distribution

4

Early Stage

16

Mid Stage

25

Late Stage

Phase Distribution58 total trials
Phase 1Safety & dosage
4(6.9%)
Phase 2Efficacy & side effects
16(27.6%)
Phase 3Large-scale testing
5(8.6%)
Phase 4Post-market surveillance
20(34.5%)
N/ANon-phased studies
13(22.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.9%

30 of 39 finished

Non-Completion Rate

23.1%

9 ended early

Currently Active

3

trials recruiting

Total Trials

61

all time

Status Distribution
Active(6)
Completed(30)
Terminated(9)
Other(16)

Detailed Status

Completed30
unknown16
Terminated7
Not yet recruiting3
Recruiting3
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
61
Active
3
Success Rate
81.1%
Most Advanced
Phase 4

Trials by Phase

Phase 14 (6.9%)
Phase 216 (27.6%)
Phase 35 (8.6%)
Phase 420 (34.5%)
N/A13 (22.4%)

Trials by Status

not_yet_recruiting35%
recruiting35%
completed3049%
unknown1626%
terminated711%
withdrawn23%

Recent Activity

Clinical Trials (61)

Showing 20 of 61 trialsScroll for more
NCT07313605Phase 1

POCUS-Guided Esmolol in Septic Shock: A Pilot RCT

Not Yet Recruiting
NCT06958393Phase 4

Effect of Opioid-free Anaesthesia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery

Not Yet Recruiting
NCT02098629Phase 2

Concomitant Milrinone and Esmolol Treatment in Patients with Acute Myocardial Infarction

Completed
NCT06620991Not Applicable

Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery

Not Yet Recruiting
NCT04356352Phase 2

Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain

Terminated
NCT06522594Phase 2

REMAP ECMO - Beta Receptor Modulation Trial

Recruiting
NCT06390748Phase 2

Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes

Completed
NCT03549923Phase 4

Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)

Completed
NCT06013319Phase 3

Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress Syndrome

Recruiting
NCT06268275Not Applicable

Comparison of Effects of Scalp Block and Intravenous Esmolol on Hemodynamic Response Following the Skull Pins Application for Elective Supratentorial Craniotomy

Completed
NCT05850832Phase 2

Efficacy of Esmolol Versus Magnesium Sulphate on Quality of Recovery in Patients Undergoing Laparoscopic Cholecystectomy: Randomized Controlled Study

Completed
NCT05635877Phase 4

Effects of Low-dose Esmolol on Myocardial Injury After Non-cardiac Surgery in Elderly Frail Patients

Recruiting
NCT05694585Phase 4

Effect of Esmolol on Perioperative Stress Reaction

Unknown
NCT05389176Not Applicable

Effects of Heart Control at Different Stages in Patients of Septic Shock With Tachycardia

Unknown
NCT05073094Phase 4

Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy

Unknown
NCT04752111Phase 4

Dose Esmolol Infusion Have an Adjuvant Effect to TAP Block for Pain Control in Laparoscopic Cholecystectomy.

Completed
NCT04948957

Changes in Cerebral Oxygenation and Cognitive Functions

Completed
NCT02369900Phase 2

Esmolol to Treat the Hemodynamic Effects of Septic Shock

Terminated
NCT03661346Phase 2

Esmolol vs. Labetalol in Endoscopic Sinus Surgery

Completed
NCT04537767Not Applicable

The Effect of Esmolol on Patients With Sepsis

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
61