Success Metrics

Clinical Success Rate
93.9%

Based on 108 completed trials

Completion Rate
94%(108/115)
Active Trials
27(15%)
Results Posted
50%(54 trials)
Terminated
7(4%)

Phase Distribution

Ph phase_3
38
22%
Ph early_phase_1
2
1%
Ph phase_2
35
20%
Ph not_applicable
9
5%
Ph phase_1
25
14%
Ph phase_4
42
24%

Phase Distribution

27

Early Stage

35

Mid Stage

80

Late Stage

Phase Distribution151 total trials
Early Phase 1First-in-human
2(1.3%)
Phase 1Safety & dosage
25(16.6%)
Phase 2Efficacy & side effects
35(23.2%)
Phase 3Large-scale testing
38(25.2%)
Phase 4Post-market surveillance
42(27.8%)
N/ANon-phased studies
9(6.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

86.4%

108 of 125 finished

Non-Completion Rate

13.6%

17 ended early

Currently Active

27

trials recruiting

Total Trials

176

all time

Status Distribution
Active(34)
Completed(108)
Terminated(17)
Other(17)

Detailed Status

Completed108
Recruiting23
unknown17
Withdrawn10
Terminated7
Not yet recruiting7

Development Timeline

Analytics

Development Status

Total Trials
176
Active
27
Success Rate
93.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (1.3%)
Phase 125 (16.6%)
Phase 235 (23.2%)
Phase 338 (25.2%)
Phase 442 (27.8%)
N/A9 (6.0%)

Trials by Status

recruiting2313%
terminated74%
unknown1710%
withdrawn106%
not_yet_recruiting74%
active_not_recruiting42%
completed10861%

Recent Activity

Clinical Trials (176)

Showing 20 of 176 trialsScroll for more
NCT06424288Phase 3

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Recruiting
NCT06935370Phase 3

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Recruiting
NCT06531824Phase 3

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

Active Not Recruiting
NCT07064473Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Recruiting
NCT07756294Phase 2

Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease

Not Yet Recruiting
NCT06926660Phase 2

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease

Completed
NCT07845630Phase 1

A Study in Healthy People to Compare How 2 Different Formulations of Vicadrostat / Empagliflozin Tablets Are Taken up in the Body

Not Yet Recruiting
NCT06435858Phase 2

Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease

Completed
NCT06149793Phase 2

SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes

Active Not Recruiting
NCT07107945Phase 3

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

Recruiting
NCT06024746Phase 3

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

Recruiting
NCT03424005Phase 1

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

Recruiting
NCT05232071Phase 2

Placebo-controlled, Proof-of-concept Study to Evaluate the Safety and Efficacy of Lanifibranor Alone and in Combination With SGLT2 Inhibitor EmpaGliflozin in patiEnts With NASH and Type 2 Diabetes Mellitus

Completed
NCT06762314Phase 2

Efficacy and Safety of Empagliflozin or Semaglutide in Overweight/Obese Patients With Type 1 Diabetes

Completed
NCT05757791Phase 2

Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2) in Major Depressive Disorder (MDD)

Completed
NCT05426525Phase 4

Use of Empagliflozin to Treat Prediabetes

Completed
NCT07060417Phase 2

Vascular Effects of SGLT2i in Non-diabetic CKD

Not Yet Recruiting
NCT07775846Phase 4

QUARTET-DKD: Quadruple Therapy for Type 2 Diabetic Nephropathy

Not Yet Recruiting
NCT05313529Not Applicable

LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes

Completed
NCT07749014Phase 2

Timing of Empagliflozin in Primary PCI: Pre-Reperfusion Versus Post-Reperfusion Versus Placebo in South Asian STEMI Patients

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
176