Success Metrics

Clinical Success Rate
93.6%

Based on 103 completed trials

Completion Rate
94%(103/110)
Active Trials
32(18%)
Results Posted
50%(51 trials)
Terminated
7(4%)

Phase Distribution

Ph phase_1
24
14%
Ph phase_2
34
20%
Ph phase_3
38
22%
Ph phase_4
41
24%
Ph early_phase_1
2
1%
Ph not_applicable
9
5%

Phase Distribution

26

Early Stage

34

Mid Stage

79

Late Stage

Phase Distribution148 total trials
Early Phase 1First-in-human
2(1.4%)
Phase 1Safety & dosage
24(16.2%)
Phase 2Efficacy & side effects
34(23.0%)
Phase 3Large-scale testing
38(25.7%)
Phase 4Post-market surveillance
41(27.7%)
N/ANon-phased studies
9(6.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.8%

103 of 120 finished

Non-Completion Rate

14.2%

17 ended early

Currently Active

32

trials recruiting

Total Trials

173

all time

Status Distribution
Active(36)
Completed(103)
Terminated(17)
Other(17)

Detailed Status

Completed103
Recruiting27
unknown17
Withdrawn10
Terminated7
Active, not recruiting5

Development Timeline

Analytics

Development Status

Total Trials
173
Active
32
Success Rate
93.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (1.4%)
Phase 124 (16.2%)
Phase 234 (23.0%)
Phase 338 (25.7%)
Phase 441 (27.7%)
N/A9 (6.1%)

Trials by Status

active_not_recruiting53%
recruiting2716%
not_yet_recruiting42%
terminated74%
withdrawn106%
completed10360%
unknown1710%

Recent Activity

Clinical Trials (173)

Showing 20 of 173 trialsScroll for more
NCT06926660Phase 2

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease

Active Not Recruiting
NCT07107945Phase 3

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

Recruiting
NCT07064473Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Recruiting
NCT06424288Phase 3

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Recruiting
NCT05313529Not Applicable

LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes

Completed
NCT06935370Phase 3

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Recruiting
NCT07749014Phase 2

Timing of Empagliflozin in Primary PCI: Pre-Reperfusion Versus Post-Reperfusion Versus Placebo in South Asian STEMI Patients

Not Yet Recruiting
NCT06024746Phase 3

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

Recruiting
NCT03363464

Comparative Effectiveness of Empagliflozin in the US

Completed
NCT03424005Phase 1

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

Recruiting
NCT05254002Phase 2

A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes

Completed
NCT07599345

Emulation of the EMPEROR-Reduced Trial Using Healthcare Claims Data

Completed
NCT07599293

Emulation of the EMPEROR-Preserved Trial Using Healthcare Claims Data

Completed
NCT06531824Phase 3

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

Recruiting
NCT05960617Phase 2

Efficacy and Safety of Empagliflozin in GSD-Ib Patients

Withdrawn
NCT07214818Phase 2

SGLT2 Inhibitors in Adult Primary Nephrotic Syndrome

Recruiting
NCT07060417Phase 2

Vascular Effects of SGLT2i in Non-diabetic CKD

Not Yet Recruiting
NCT06171802Phase 4

EMPagliflozin After Aortic Valve Replacement

Completed
NCT06571591Phase 3

Efficacy and Safety of Pioglitazone Combination Therapy in Type 2 Diabetes Patients on a Background of Empagliflozin With Metformin

Completed
NCT06844669Phase 2

HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
173