Success Metrics

Clinical Success Rate
100.0%

Based on 19 completed trials

Completion Rate
100%(19/19)
Active Trials
2(9%)
Results Posted
89%(17 trials)

Phase Distribution

Ph phase_3
21
91%

Phase Distribution

0

Early Stage

0

Mid Stage

21

Late Stage

Phase Distribution21 total trials
Phase 3Large-scale testing
21(100.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

19 of 19 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

2

trials recruiting

Total Trials

23

all time

Status Distribution
Active(2)
Completed(19)
Other(2)

Detailed Status

Completed19
unknown2
Active, not recruiting2

Development Timeline

Analytics

Development Status

Total Trials
23
Active
2
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 321 (100.0%)

Trials by Status

unknown29%
active_not_recruiting29%
completed1983%

Recent Activity

Clinical Trials (23)

Showing 20 of 23 trialsScroll for more
NCT05153317Phase 3

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older

Completed
NCT05331183Phase 3

Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del

Active Not Recruiting
NCT06460506Phase 3

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older

Active Not Recruiting
NCT05882357Phase 3

Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age

Completed
NCT03525574Phase 3

A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Completed
NCT04969224Phase 3

A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF)

Completed
NCT04183790Phase 3

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA TC Combination Therapy in Participants With Cystic Fibrosis Who Are 6 Years of Age and Older

Completed
NCT05033080Phase 3

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Completed
NCT05274269Phase 3

Evaluation of Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis Subjects Without an F508del Mutation

Completed
NCT05076149Phase 3

A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation

Completed
NCT04545515Phase 3

A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (CF) Particpants 6 Years and Older and F/MF Genotypes

Completed
NCT04058366Phase 3

Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Completed
NCT04599465Phase 3

A Study to Assess the Effect of ELX/TEZ/IVA on Glucose Tolerance in Participants With Cystic Fibrosis (CF)

Completed
NCT04362761Phase 3

A Study Evaluating the Long-Term Safety of Elexacaftor Combination Therapy

Completed
NCT05111145Phase 3

A Study Evaluating the Safety of Elexacaftor/Tezacaftor/Ivacaftor in Participants With Cystic Fibrosis (CF)

Completed
NCT04043806Phase 3

A Study Evaluating the Long-term Safety of VX-445 Combination Therapy

Completed
NCT04537793Phase 3

Evaluation of ELX/TEZ/IVA in Cystic Fibrosis (CF) Subjects 2 Through 5 Years

Completed
NCT04353817Phase 3

A Study Evaluating Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis and F/MF Genotypes

Completed
NCT03691779Phase 3

Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age

Completed
NCT04105972Phase 3

A Study Evaluating the Efficacy and Safety of VX-445/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects, Homozygous for F508del

Completed

Drug Details

Intervention Type
DRUG
Total Trials
23