Success Metrics

Clinical Success Rate
76.7%

Based on 33 completed trials

Completion Rate
77%(33/43)
Active Trials
6(10%)
Results Posted
48%(16 trials)
Terminated
10(16%)

Phase Distribution

Ph phase_2
10
16%
Ph phase_3
15
24%
Ph phase_4
15
24%
Ph phase_1
6
10%

Phase Distribution

6

Early Stage

10

Mid Stage

30

Late Stage

Phase Distribution46 total trials
Phase 1Safety & dosage
6(13.0%)
Phase 2Efficacy & side effects
10(21.7%)
Phase 3Large-scale testing
15(32.6%)
Phase 4Post-market surveillance
15(32.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.0%

33 of 50 finished

Non-Completion Rate

34.0%

17 ended early

Currently Active

6

trials recruiting

Total Trials

62

all time

Status Distribution
Active(8)
Completed(33)
Terminated(17)
Other(4)

Detailed Status

Completed33
Terminated10
Withdrawn7
Recruiting4
unknown4
Active, not recruiting2

Development Timeline

Analytics

Development Status

Total Trials
62
Active
6
Success Rate
76.7%
Most Advanced
Phase 4

Trials by Phase

Phase 16 (13.0%)
Phase 210 (21.7%)
Phase 315 (32.6%)
Phase 415 (32.6%)

Trials by Status

enrolling_by_invitation12%
withdrawn711%
active_not_recruiting23%
completed3353%
recruiting46%
not_yet_recruiting12%
terminated1016%
unknown46%

Recent Activity

Clinical Trials (62)

Showing 20 of 62 trialsScroll for more
NCT04381936Phase 3

Randomised Evaluation of COVID-19 Therapy

Recruiting
NCT07483632Phase 3

A Study to Learn About the Safety of Diroximel Fumarate (DRF) and Dimethyl Fumarate (DMF) and Their Effects on Relapses in Pediatric Participants With Relapsing Forms of Multiple Sclerosis (RMS)

Not Yet Recruiting
NCT05767736

A Study to Evaluate Long-Term Safety of Vumerity and Tecfidera in Participants With Multiple Sclerosis (MS)

Active Not Recruiting
NCT05658497

Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)

Recruiting
NCT02283853Phase 3

Phase 3 Efficacy and Safety Study of BG00012 in Pediatric Subjects With Relapsing-remitting Multiple Sclerosis (RRMS)

Completed
NCT05658484Phase 4

A Study of Dimethyl Fumarate (DMF) in Relapsing Forms of Multiple Sclerosis (RMS) Participants in China

Completed
NCT06850597Phase 2

Efficacy and Safety of Dimethyl Fumarate Among Patients with Mild Cognitive Impairment and Dementia Due to Alzheimer's Disease

Recruiting
NCT06513533Phase 2

Dimethyl Fumarate in Adrenomyeloneuropathy

Recruiting
NCT05417269Phase 1

IMCY-0141 Safety and Efficacy in Multiple Sclerosis - ISEMIS Study

Active Not Recruiting
NCT04890379Phase 2

Dimethyl Fumarate for the Treatment of Intracerebral Hemorrhage

Withdrawn
NCT04891497Phase 2

Combination of the Immune Modulator Dimethyl Fumarate With Intraarterial Treatment in Acute Ischemic Stroke

Withdrawn
NCT04890353Phase 1

Impact of an Immune Modulator Dimethyl Fumarate on Acute Ischemic Stroke

Terminated
NCT04756687

Real World Analysis on Lymphocyte Reconstitution After Lymphopenia in Participants Treated by Tecfidera

Completed
NCT04221191

Dimethyl Fumarate (DMF, Tecfidera®) Persistence in RR-MS Patients Included in the French Patient Support Program OroSEP

Completed
NCT05959759Phase 4

Dimethyl Fumarate Treatment for Intracranial Unruptured Aneurysms.

Unknown
NCT03870763Phase 3

Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and Peginterferon Beta-1a (Plegridy) for the Treatment of Relapsing-Remitting Multiple Sclerosis in Pediatric Participants

Terminated
NCT02047097

Dimethyl Fumarate (DMF) Observational Study

Completed
NCT02546440Phase 2

Study on Therapy With Dimethylfumarate (DMF) in Patients With Cutaneous T Cell Lymphoma (CTCL)

Completed
NCT04676204

Relationship Between Oral DMT Burden and Adherence in MS

Enrolling By Invitation
NCT01911767

Biogen Multiple Sclerosis Pregnancy Exposure Registry

Completed

Drug Details

Intervention Type
DRUG
Total Trials
62