Success Metrics

Clinical Success Rate
87.5%

Based on 28 completed trials

Completion Rate
88%(28/32)
Active Trials
5(13%)
Results Posted
36%(10 trials)
Terminated
4(10%)

Phase Distribution

Ph phase_2
5
13%
Ph early_phase_1
2
5%
Ph phase_1
17
43%
Ph phase_3
4
10%
Ph phase_4
1
3%
Ph not_applicable
10
25%

Phase Distribution

19

Early Stage

5

Mid Stage

5

Late Stage

Phase Distribution39 total trials
Early Phase 1First-in-human
2(5.1%)
Phase 1Safety & dosage
17(43.6%)
Phase 2Efficacy & side effects
5(12.8%)
Phase 3Large-scale testing
4(10.3%)
Phase 4Post-market surveillance
1(2.6%)
N/ANon-phased studies
10(25.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

82.4%

28 of 34 finished

Non-Completion Rate

17.6%

6 ended early

Currently Active

5

trials recruiting

Total Trials

40

all time

Status Distribution
Active(5)
Completed(28)
Terminated(6)
Other(1)

Detailed Status

Completed28
Terminated4
Recruiting3
Active, not recruiting2
Withdrawn2
unknown1

Development Timeline

Analytics

Development Status

Total Trials
40
Active
5
Success Rate
87.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (5.1%)
Phase 117 (43.6%)
Phase 25 (12.8%)
Phase 34 (10.3%)
Phase 41 (2.6%)
N/A10 (25.6%)

Trials by Status

completed2870%
terminated410%
active_not_recruiting25%
recruiting38%
unknown13%
withdrawn25%

Recent Activity

Clinical Trials (40)

Showing 20 of 40 trialsScroll for more
NCT03035331Phase 1

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

Completed
NCT04693377Not Applicable

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Recruiting
NCT04150939Not Applicable

Cryoablation for the Treatment of Metastatic Cancer

Active Not Recruiting
NCT06593106Not Applicable

Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

Recruiting
NCT03325101Phase 1

Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma

Terminated
NCT06178354Not Applicable

Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer

Recruiting
NCT00110110Phase 2

Combination Chemotherapy and Cyclosporine Followed by Focal Therapy for Bilateral Retinoblastoma

Active Not Recruiting
NCT00002997Phase 2

Cryosurgery in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer

Completed
NCT00079417Phase 3

Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma

Completed
NCT04249167Early Phase 1

Cryoablation, Atezolizumab/Nab-paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer

Withdrawn
NCT02626130Early Phase 1

Tremelimumab With or Without Cryoablation in Treating Patients With Metastatic Kidney Cancer

Completed
NCT02489357Not Applicable

Pembrolizumab and Cryosurgery in Treating Patients With Newly Diagnosed, Oligo-metastatic Prostate Cancer

Completed
NCT00072384Phase 3

Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma

Completed
NCT04429204Not Applicable

Cryoablation for the Promotion of Local Tumor Infiltration in Patients With Mesothelioma

Withdrawn
NCT02736760Phase 4

Daylight-PDT With MAL for AK and Photodamaged Skin

Completed
NCT00303901Not Applicable

Cryotherapy in Treating Patients With Primary Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery

Completed
NCT00514215Phase 2

Cryotherapy and GM-CSF in Treating Patients With Lung Metastases or Primary Lung Cancer

Completed
NCT02843802Phase 1

Combination of Cryosurgery and NK Immunotherapy for Advanced Liver Cancer

Completed
NCT02849314Phase 1

Combination of Cryosurgey and NK Immunotherapy for Recurrent Laryngeal Cancer

Completed
NCT02849015Phase 1

Combination of Cryosurgery and NK Immunotherapy for Tumors in Transplanted Liver

Completed

Drug Details

Intervention Type
PROCEDURE
Total Trials
40