Success Metrics

Completion Rate
0%(0/1)
Active Trials
181(88%)
Terminated
1(0%)

Phase Distribution

Ph phase_1
73
36%
Ph not_applicable
3
1%
Ph phase_2
120
59%
Ph phase_3
6
3%
Ph early_phase_1
3
1%

Phase Distribution

76

Early Stage

120

Mid Stage

6

Late Stage

Phase Distribution205 total trials
Early Phase 1First-in-human
3(1.5%)
Phase 1Safety & dosage
73(35.6%)
Phase 2Efficacy & side effects
120(58.5%)
Phase 3Large-scale testing
6(2.9%)
N/ANon-phased studies
3(1.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

0.0%

0 of 4 finished

Non-Completion Rate

100.0%

4 ended early

Currently Active

181

trials recruiting

Total Trials

205

all time

Status Distribution
Active(192)
Terminated(4)
Other(9)

Detailed Status

Recruiting93
Active, not recruiting88
Not yet recruiting10
Suspended9
Withdrawn3
Enrolling by invitation1

Development Timeline

Analytics

Development Status

Total Trials
205
Active
181
Success Rate
0.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 13 (1.5%)
Phase 173 (35.6%)
Phase 2120 (58.5%)
Phase 36 (2.9%)
N/A3 (1.5%)

Trials by Status

not_yet_recruiting105%
active_not_recruiting8843%
withdrawn31%
suspended94%
enrolling_by_invitation10%
terminated10%
recruiting9345%

Recent Activity

Clinical Trials (205)

Showing 20 of 205 trialsScroll for more
NCT05099003Phase 1

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Recruiting
NCT05136196Phase 2

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Recruiting
NCT06126276Phase 2

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Recruiting
NCT06102902Phase 1

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

Recruiting
NCT06357988Phase 2

Testing GDC-0449 (Vismodegib) as Potentially Targeted Treatment in Cancers With Smoothened or Patched 1 Mutant Tumors (MATCH - Subprotocol T)

Active Not Recruiting
NCT06784726Phase 2

Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT07544992Phase 1

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

Recruiting
NCT07281417Phase 2

Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

Recruiting
NCT05304585Phase 3

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

Recruiting
NCT06400238Phase 2

Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Expression (MATCH - Subprotocol Z1H)

Active Not Recruiting
NCT03067181Phase 3

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Recruiting
NCT05490771Phase 2

Testing Copanlisib as a Potential Targeted Treatment in Cancers With PIK3CA Mutations (MATCH-Subprotocol Z1F)

Active Not Recruiting
NCT06390865Phase 2

Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With TSC1 or TSC2 Genetic Changes (MATCH - Subprotocol M)

Active Not Recruiting
NCT06390852Phase 2

Testing LOXO-101 as Potentially Targeted Treatment in Cancers With NTRK Genetic Changes (MATCH - Subprotocol Z1E)

Active Not Recruiting
NCT01947023Phase 1

Dabrafenib and Lapatinib in Treating Patients With Refractory Thyroid Cancer That Cannot Be Removed by Surgery

Active Not Recruiting
NCT05521698Phase 1

A Randomized Trial of Bicalutamide in Non-Muscle Invasive Bladder Cancer

Recruiting
NCT06400225Phase 2

Testing BVD-523FB (Ulixertinib) as Potentially Targeted Treatment in Cancers With Genetic Changes (MATCH - Subprotocol Z1L)

Active Not Recruiting
NCT03155620Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Active Not Recruiting
NCT03317392Phase 1

Different Doses of Olaparib Given With Radium-223 in Men With Advanced Prostate Cancer With Bone Metastasis

Active Not Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
205