Success Metrics

Clinical Success Rate
90.1%

Based on 73 completed trials

Completion Rate
90%(73/81)
Active Trials
2(2%)
Results Posted
60%(44 trials)
Terminated
8(8%)

Phase Distribution

Ph not_applicable
25
24%
Ph phase_2
24
23%
Ph phase_3
23
22%
Ph phase_1
11
11%
Ph phase_4
19
18%
Ph early_phase_1
1
1%

Phase Distribution

12

Early Stage

24

Mid Stage

42

Late Stage

Phase Distribution103 total trials
Early Phase 1First-in-human
1(1.0%)
Phase 1Safety & dosage
11(10.7%)
Phase 2Efficacy & side effects
24(23.3%)
Phase 3Large-scale testing
23(22.3%)
Phase 4Post-market surveillance
19(18.4%)
N/ANon-phased studies
25(24.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

84.9%

73 of 86 finished

Non-Completion Rate

15.1%

13 ended early

Currently Active

2

trials recruiting

Total Trials

104

all time

Status Distribution
Active(4)
Completed(73)
Terminated(13)
Other(14)

Detailed Status

Completed73
unknown14
Terminated8
Withdrawn5
Not yet recruiting2
Recruiting2

Development Timeline

Analytics

Development Status

Total Trials
104
Active
2
Success Rate
90.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.0%)
Phase 111 (10.7%)
Phase 224 (23.3%)
Phase 323 (22.3%)
Phase 419 (18.4%)
N/A25 (24.3%)

Trials by Status

terminated88%
withdrawn55%
completed7370%
not_yet_recruiting22%
recruiting22%
unknown1413%

Recent Activity

Clinical Trials (104)

Showing 20 of 104 trialsScroll for more
NCT04606264Phase 3

Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data

Completed
NCT06357234Phase 2

Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery

Recruiting
NCT04649229Phase 4

Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 3

Completed
NCT03718039Phase 2

Phase 2 Bunionectomy HTX-011 Administration Study

Completed
NCT07371728Phase 4

Effect of Aprepitant on Post-operative Nausea and Vomiting in Otologic Surgery

Not Yet Recruiting
NCT01963793Phase 2

Topical Aprepitant in Prurigo Patients

Completed
NCT00719173Phase 1

Effect of Aprepitant on Cyclophosphamide Pharmacokinetics in Patients With Breast Cancer

Completed
NCT01186029Not Applicable

Comparison of Adding EMEND to PONV/PDNV Treatment Regimen

Withdrawn
NCT01851369Phase 1

TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas

Completed
NCT06080880Not Applicable

Ondanstron Weekly vs Every 3 Weeks for Prevention of Nausea and Vomiting Induced by Chemotherapy Combined With PD-1 Blockade

Recruiting
NCT01020903Not Applicable

Aprepitant for Post-operative Nausea

Completed
NCT05841849Phase 4

Efficacy and Safety of Intravenous Versus Oral 5-HT3 Antagonists Combined With NK-1 Receptor Antagonists for the Prevention of CINV in Breast Cancer

Not Yet Recruiting
NCT05772676Phase 4

The Effect of Aprepitant Reducing Postoperative Nausea and Vomiting

Unknown
NCT01298193Phase 4

Incidence of Chemotherapy-Induced Nausea and Vomiting Associated With Docetaxel-Cyclophosphamide in Early Breast Cancer.

Completed
NCT03674294Phase 3

Aprepitant Triple Therapy for the Prevention of CINV in Nondrinking and Young Women Who Received Moderately Emetogenic Chemotherapy

Completed
NCT05632224Phase 4

Postoperative Nausea and Vomiting in Laparoscopic Abdominal Surgery

Unknown
NCT05346731Phase 3

Low Dose Olanzapine to the Prophylaxis of Nausea and Vomiting Induced by Chemotherapy in Children and Adolescents

Unknown
NCT02336750Phase 3

Adding Mirtazapine to Dexamethasone and Aprepitant for Delayed Emesis

Completed
NCT02130687Not Applicable

Effect of Chronic ACE and DPP4 Inhibition on Blood Pressure

Completed
NCT01334086Phase 2

Aprepitant as Antiemetic Prophylaxis in Patients With Acute Myeloid Leukemia Undergoing Induction Chemotherapy

Completed

Drug Details

Intervention Type
DRUG
Total Trials
104