Success Metrics

Clinical Success Rate
78.9%

Based on 30 completed trials

Completion Rate
79%(30/38)
Active Trials
46(48%)
Results Posted
67%(20 trials)
Terminated
8(8%)

Phase Distribution

Ph not_applicable
2
2%
Ph phase_4
2
2%
Ph phase_1
15
16%
Ph phase_3
19
20%
Ph phase_2
44
46%

Phase Distribution

15

Early Stage

44

Mid Stage

21

Late Stage

Phase Distribution82 total trials
Phase 1Safety & dosage
15(18.3%)
Phase 2Efficacy & side effects
44(53.7%)
Phase 3Large-scale testing
19(23.2%)
Phase 4Post-market surveillance
2(2.4%)
N/ANon-phased studies
2(2.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

69.8%

30 of 43 finished

Non-Completion Rate

30.2%

13 ended early

Currently Active

46

trials recruiting

Total Trials

95

all time

Status Distribution
Active(49)
Completed(30)
Terminated(13)
Other(3)

Detailed Status

Completed30
Active, not recruiting25
Recruiting21
Terminated8
Withdrawn5
unknown3

Development Timeline

Analytics

Development Status

Total Trials
95
Active
46
Success Rate
78.9%
Most Advanced
Phase 4

Trials by Phase

Phase 115 (18.3%)
Phase 244 (53.7%)
Phase 319 (23.2%)
Phase 42 (2.4%)
N/A2 (2.4%)

Trials by Status

recruiting2122%
unknown33%
withdrawn55%
not_yet_recruiting33%
completed3032%
terminated88%
active_not_recruiting2526%

Recent Activity

Clinical Trials (95)

Showing 20 of 95 trialsScroll for more
NCT04423211Phase 3

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

Recruiting
NCT06095089Phase 1

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

Recruiting
NCT04513717Phase 3

Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial

Active Not Recruiting
NCT03436654Phase 2

Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Metastatic Prostatic Adenocarcinoma

Active Not Recruiting
NCT06274047Phase 3

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

Recruiting
NCT04530552Phase 2

Testing the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate Gland

Active Not Recruiting
NCT04523207Phase 2

A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for Metastases

Completed
NCT06378866Phase 2

Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

Recruiting
NCT02913196Phase 1

Phase I Trial of Apalutamide Plus Abiraterone Acetate, Docetaxel, and Prednisone in Patients With mCRPC

Completed
NCT03821792Phase 2

Abiraterone Acetate, Prednisone, and Apalutamide in Treating Patients With Hormone-Naive Metastatic Prostate Cancer

Active Not Recruiting
NCT07002320Phase 1

Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant Prostate Cancer

Recruiting
NCT06592924Phase 3

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Recruiting
NCT05960578Phase 2

Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study

Active Not Recruiting
NCT02489318Phase 3

A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPC

Active Not Recruiting
NCT04557059Phase 3

A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer

Active Not Recruiting
NCT04662580Phase 1

ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer

Active Not Recruiting
NCT05901649

A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or Enzalutamide

Active Not Recruiting
NCT01946204Phase 3

A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer

Active Not Recruiting
NCT04325828Phase 2

A Study of Apalutamide Combined With GnRH Agonist in Participants With Androgen Receptor Positive Salivary Gland Carcinoma

Active Not Recruiting
NCT05818683Phase 1

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
95