Success Metrics

Clinical Success Rate
80.5%

Based on 33 completed trials

Completion Rate
80%(33/41)
Active Trials
46(47%)
Results Posted
64%(21 trials)
Terminated
8(8%)

Phase Distribution

Ph phase_2
45
46%
Ph not_applicable
2
2%
Ph phase_3
20
21%
Ph phase_1
15
15%
Ph phase_4
2
2%

Phase Distribution

15

Early Stage

45

Mid Stage

22

Late Stage

Phase Distribution84 total trials
Phase 1Safety & dosage
15(17.9%)
Phase 2Efficacy & side effects
45(53.6%)
Phase 3Large-scale testing
20(23.8%)
Phase 4Post-market surveillance
2(2.4%)
N/ANon-phased studies
2(2.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.7%

33 of 46 finished

Non-Completion Rate

28.3%

13 ended early

Currently Active

46

trials recruiting

Total Trials

97

all time

Status Distribution
Active(48)
Completed(33)
Terminated(13)
Other(3)

Detailed Status

Completed33
Active, not recruiting24
Recruiting22
Terminated8
Withdrawn5
unknown3

Development Timeline

Analytics

Development Status

Total Trials
97
Active
46
Success Rate
80.5%
Most Advanced
Phase 4

Trials by Phase

Phase 115 (17.9%)
Phase 245 (53.6%)
Phase 320 (23.8%)
Phase 42 (2.4%)
N/A2 (2.4%)

Trials by Status

terminated88%
recruiting2223%
unknown33%
active_not_recruiting2425%
withdrawn55%
not_yet_recruiting22%
completed3334%

Recent Activity

Clinical Trials (97)

Showing 20 of 97 trialsScroll for more
NCT06931340Phase 3

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

Recruiting
NCT07745361Phase 2

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

Recruiting
NCT01946204Phase 3

A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer

Active Not Recruiting
NCT05884398Phase 3

A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPC

Active Not Recruiting
NCT06095089Phase 1

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

Recruiting
NCT03767244Phase 3

A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

Active Not Recruiting
NCT05901649

A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or Enzalutamide

Completed
NCT04108208Phase 4

A Study of Apalutamide in Chinese Participants With Non Metastatic Castration Resistant Prostate Cancer (NM-CRPC)

Completed
NCT06274047Phase 3

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

Recruiting
NCT06378866Phase 2

Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

Recruiting
NCT06067269Phase 2

Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial

Recruiting
NCT04267887Phase 2

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Active Not Recruiting
NCT06592924Phase 3

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Recruiting
NCT03371719Phase 2

Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Trial

Active Not Recruiting
NCT07406282

A Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology Clinics

Recruiting
NCT04557059Phase 3

A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer

Active Not Recruiting
NCT04662580Phase 1

ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer

Active Not Recruiting
NCT02257736Phase 3

An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)

Active Not Recruiting
NCT02531516Phase 3

An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS

Active Not Recruiting
NCT05818683Phase 1

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
97