Success Metrics

Clinical Success Rate
83.0%

Based on 112 completed trials

Completion Rate
83%(112/135)
Active Trials
44(21%)
Results Posted
71%(79 trials)
Terminated
23(11%)

Phase Distribution

Ph phase_4
10
5%
Ph not_applicable
14
7%
Ph phase_2
86
41%
Ph early_phase_1
2
1%
Ph phase_1
22
11%
Ph phase_3
57
27%

Phase Distribution

24

Early Stage

86

Mid Stage

67

Late Stage

Phase Distribution191 total trials
Early Phase 1First-in-human
2(1.0%)
Phase 1Safety & dosage
22(11.5%)
Phase 2Efficacy & side effects
86(45.0%)
Phase 3Large-scale testing
57(29.8%)
Phase 4Post-market surveillance
10(5.2%)
N/ANon-phased studies
14(7.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.9%

112 of 142 finished

Non-Completion Rate

21.1%

30 ended early

Currently Active

44

trials recruiting

Total Trials

209

all time

Status Distribution
Active(47)
Completed(112)
Terminated(30)
Other(20)

Detailed Status

Completed112
Terminated23
Active, not recruiting22
Recruiting22
unknown17
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
209
Active
44
Success Rate
83.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (1.0%)
Phase 122 (11.5%)
Phase 286 (45.0%)
Phase 357 (29.8%)
Phase 410 (5.2%)
N/A14 (7.3%)

Trials by Status

completed11254%
active_not_recruiting2211%
recruiting2211%
suspended31%
withdrawn73%
not_yet_recruiting21%
enrolling_by_invitation10%
terminated2311%
unknown178%

Recent Activity

Clinical Trials (209)

Showing 20 of 209 trialsScroll for more
NCT05952557Phase 3

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Active Not Recruiting
NCT06930859

Non-interventional Study to Assess the Effectiveness and Safety of Ribociclib in the Adjuvant Therapy of Hormone Receptor Positive (HR+) HER2-negative Stage II and III Breast Cancer in Real Clinical Practice in Russia

Recruiting
NCT07391774Phase 3

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Recruiting
NCT02206984Phase 2

Endocrine Response in Women With Invasive Lobular Breast Cancer

Completed
NCT07174336Phase 3

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Recruiting
NCT06671912Phase 3

Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial

Suspended
NCT01272037Phase 3

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Active Not Recruiting
NCT04556773Phase 1

A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer

Active Not Recruiting
NCT06072781Phase 3

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Recruiting
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT06380751Phase 3

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Recruiting
NCT03304080Phase 1

Anastrozole, Palbociclib, Trastuzumab and Pertuzumab in HR-positive, HER2-positive Metastatic Breast

Active Not Recruiting
NCT02476786Phase 2

Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score

Recruiting
NCT02942355Phase 2

Trial of Anastrozole and Palbociclib in Metastatic HER2-Negative Breast Cancer

Active Not Recruiting
NCT07716046Phase 2

Fulvestaciclib Combined With Anti-HER2 and Endocrine Therapy for HR+/HER2+ Advanced Breast Cancer

Not Yet Recruiting
NCT05774951Phase 3

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Recruiting
NCT04719273Phase 2

Onapristone and Anastrozole for the Treatment of Refractory Hormone Receptor Positive Endometrial Cancer

Completed
NCT04469764Phase 2

Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer

Recruiting
NCT05467891Phase 2

Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

Recruiting
NCT04964934Phase 3

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
209