Success Metrics

Clinical Success Rate
83.0%

Based on 112 completed trials

Completion Rate
83%(112/135)
Active Trials
44(21%)
Results Posted
72%(81 trials)
Terminated
23(11%)

Phase Distribution

Ph phase_2
86
41%
Ph phase_3
57
27%
Ph phase_4
10
5%
Ph phase_1
22
11%
Ph early_phase_1
2
1%
Ph not_applicable
14
7%

Phase Distribution

24

Early Stage

86

Mid Stage

67

Late Stage

Phase Distribution191 total trials
Early Phase 1First-in-human
2(1.0%)
Phase 1Safety & dosage
22(11.5%)
Phase 2Efficacy & side effects
86(45.0%)
Phase 3Large-scale testing
57(29.8%)
Phase 4Post-market surveillance
10(5.2%)
N/ANon-phased studies
14(7.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.9%

112 of 142 finished

Non-Completion Rate

21.1%

30 ended early

Currently Active

44

trials recruiting

Total Trials

209

all time

Status Distribution
Active(47)
Completed(112)
Terminated(30)
Other(20)

Detailed Status

Completed112
Active, not recruiting23
Terminated23
Recruiting21
unknown17
Withdrawn7

Development Timeline

Analytics

Development Status

Total Trials
209
Active
44
Success Rate
83.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (1.0%)
Phase 122 (11.5%)
Phase 286 (45.0%)
Phase 357 (29.8%)
Phase 410 (5.2%)
N/A14 (7.3%)

Trials by Status

not_yet_recruiting21%
unknown178%
active_not_recruiting2311%
suspended31%
terminated2311%
completed11254%
enrolling_by_invitation10%
withdrawn73%
recruiting2110%

Recent Activity

Clinical Trials (209)

Showing 20 of 209 trialsScroll for more
NCT07391774Phase 3

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Recruiting
NCT05161195Phase 4

Roll-over Study to Allow Continued Access to Ribociclib

Active Not Recruiting
NCT00310180Phase 3

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)

Active Not Recruiting
NCT01272037Phase 3

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Active Not Recruiting
NCT04711252Phase 3

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease

Active Not Recruiting
NCT02188745Phase 2

ER Reactivation Therapy for Breast Cancer

Completed
NCT01723774Phase 2

PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer

Active Not Recruiting
NCT06253702Phase 4

Brain Blood Flow Responses to Stress: Sex Differences

Completed
NCT06179303Phase 2

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Recruiting
NCT04964934Phase 3

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

Active Not Recruiting
NCT07174336Phase 3

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Recruiting
NCT06492616Phase 3

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Recruiting
NCT06671912Phase 3

Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial

Suspended
NCT06380751Phase 3

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Recruiting
NCT06086704Phase 2

Study of 18F-FFNP Breast PET/MRI

Recruiting
NCT01824836Not Applicable

A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)

Active Not Recruiting
NCT05501704Phase 2

ETHAN - ET for Male BC

Recruiting
NCT05774951Phase 3

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Recruiting
NCT06072781Phase 3

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Recruiting
NCT06016738Phase 3

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
209