Success Metrics

Clinical Success Rate
53.3%

Based on 8 completed trials

Completion Rate
53%(8/15)
Active Trials
0(0%)
Results Posted
138%(11 trials)
Terminated
7(44%)

Phase Distribution

Ph phase_1
8
50%
Ph phase_3
1
6%
Ph phase_2
7
44%

Phase Distribution

8

Early Stage

7

Mid Stage

1

Late Stage

Phase Distribution16 total trials
Phase 1Safety & dosage
8(50.0%)
Phase 2Efficacy & side effects
7(43.8%)
Phase 3Large-scale testing
1(6.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

8 of 16 finished

Non-Completion Rate

50.0%

8 ended early

Currently Active

0

trials recruiting

Total Trials

16

all time

Status Distribution
Completed(8)
Terminated(8)

Detailed Status

Completed8
Terminated7
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
16
Active
0
Success Rate
53.3%
Most Advanced
Phase 3

Trials by Phase

Phase 18 (50.0%)
Phase 27 (43.8%)
Phase 31 (6.3%)

Trials by Status

completed850%
withdrawn16%
terminated744%

Recent Activity

Clinical Trials (16)

Showing 16 of 16 trials
NCT01318642Phase 2

Ganitumab in Locally Advanced Unresectable Adenocarcinoma of the Pancreas

Terminated
NCT00630552Phase 1

QUILT-2.019: A Study of AMG 655 or AMG 479 in Combination With Gemcitabine for Treatment of Metastatic Pancreatic Cancer

Completed
NCT00807612Phase 1

QUILT-2.017: Phase 1b/2 Study of AMG 479 in Combination With Paclitaxel and Carboplatin for 1st Line Treatment of Advanced Squamous Non-Small Cell Lung Cancer

Terminated
NCT00626106Phase 2

QUILT-2.015: A Study of AMG 479 With Exemestane or Fulvestrant in Postmenopausal Women With Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer

Completed
NCT00791154Phase 1

QUILT-2.013: First-Line Treatment for Extensive Stage Small Cell Lung Cancer

Terminated
NCT00819169Phase 1

QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors

Terminated
NCT01231347Phase 3

QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas

Completed
NCT01562899Phase 1

A Study of MEK162 and AMG 479 in Patients With Selected Solid Tumors

Terminated
NCT01708161Phase 1

A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors

Terminated
NCT01024387Phase 2

AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors

Completed
NCT00813605Phase 2

QUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma

Completed
NCT00974896Phase 1

QUILT-2.016: Study of AMG 479 With Biologics or Chemotherapy for Subjects With Advanced Solid Tumors

Completed
NCT00563680Phase 2

QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors

Completed
NCT01479179Phase 1

Trastuzumab in Combination With AMG 479 in HER-2 Overexpressing MBC Progressing on Trastuzumab

Withdrawn
NCT00718523Phase 2

Study of Adding AMG 479 to First Line Chemotherapy in Patients With Optimally Debulked Epithelial Ovarian Cancer

Terminated
NCT00719212Phase 2

Study of AMG 479 as Second Line Therapy in Patients With Recurrent Platinum-sensitive Ovarian Cancer

Completed

All 16 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
16