Success Metrics

Clinical Success Rate
66.7%

Based on 6 completed trials

Completion Rate
67%(6/9)
Active Trials
5(23%)
Results Posted
33%(2 trials)
Terminated
3(14%)

Phase Distribution

Ph not_applicable
1
5%
Ph phase_1
5
23%
Ph phase_3
4
18%
Ph phase_2
12
55%

Phase Distribution

5

Early Stage

12

Mid Stage

4

Late Stage

Phase Distribution22 total trials
Phase 1Safety & dosage
5(22.7%)
Phase 2Efficacy & side effects
12(54.5%)
Phase 3Large-scale testing
4(18.2%)
N/ANon-phased studies
1(4.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

66.7%

6 of 9 finished

Non-Completion Rate

33.3%

3 ended early

Currently Active

5

trials recruiting

Total Trials

22

all time

Status Distribution
Active(7)
Completed(6)
Terminated(3)
Other(6)

Detailed Status

Completed6
unknown6
Recruiting4
Terminated3
Not yet recruiting1
Enrolling by invitation1

Development Timeline

Analytics

Development Status

Total Trials
22
Active
5
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Phase 15 (22.7%)
Phase 212 (54.5%)
Phase 34 (18.2%)
N/A1 (4.5%)

Trials by Status

completed627%
not_yet_recruiting15%
terminated314%
enrolling_by_invitation15%
active_not_recruiting15%
recruiting418%
unknown627%

Recent Activity

Clinical Trials (22)

Showing 20 of 22 trialsScroll for more
NCT05345002Phase 2

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Recruiting
NCT04113863Phase 2

Evaluation of ATRA Activity in Combination With Anastrozole in Pre-operative Phase of Operable Early Breast Cancer

Terminated
NCT06439888Phase 1

Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer

Recruiting
NCT06528769Phase 2

Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma

Recruiting
NCT07187505Not Applicable

Venetoclax Combined With ATRA and ATO in Hyperleukocytic Acute Promyelocytic Leukemia

Active Not Recruiting
NCT05438875Phase 3

The Combination of ATRA and Eltrombopag as the Treatment of Steroid-resistant/Relapse ITP Based on MSC-C5b-9

Completed
NCT03031249Phase 1

Efficacy and Safety of ATO Plus ATRA in Nucleophosmin-1 Mutated Acute Myeloid Leukemia

Enrolling By Invitation
NCT04700176Phase 2

A Study of Daratumumab With Pomalidomide, Dexamethasone, and All-Transretinoic Acid in Patients With Multiple Myeloma

Terminated
NCT06646666Phase 2

ARTA-based Chemo-free Bridging/Maintenance Therapy in CAR-T Treatment for High-Risk R/R B-NHL Ineligible for HDCT and ASCT

Not Yet Recruiting
NCT04793919Phase 2

Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia

Recruiting
NCT05497310Phase 1

Effectiveness and Safety of Therapy Based on Attenuated ATO Plus Low-Dose ATRA in Patients With APL

Unknown
NCT00482833Phase 3

Phase III Trial in Acute Promyelocytic Leukemia Patients

Completed
NCT05297123Phase 1

Treatment of Acute Myeloid Leukemia With Arsenic and All-trans Retinoid Acid

Unknown
NCT02899169Phase 3

Treatment of Non-high-risk Acute Promyelocytic Leukemia (APL) With Realgar-Indigo Naturalis Formula (RIF)

Unknown
NCT03359174Phase 2

An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis

Terminated
NCT04433169Phase 2

All-trans Retinoic Acid (ATRA) in the Treatment of Recurrent/Metastatic Adenoid Cystic Carcinoma of the Head and Neck

Unknown
NCT03304288Phase 2

The Combination of Low-dose Rituximab and ATRA as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Unknown
NCT02717884Phase 1

Study of Sensitization of Non-M3 AML Blasts to ATRA by Epigenetic Treatment With Tranylcypromine (TCP)

Unknown
NCT00151242Phase 2

Study on All-Trans Retinoic Acid, Induction and Consolidation Therapy, and Pegfilgrastim After Consolidation Therapy in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia

Completed
NCT01667263Phase 2

The Combination of ATRA and Danazol as Second-line Treatment in Adult Immune Thrombocytopenia

Completed

Drug Details

Intervention Type
DRUG
Total Trials
22