Key Insights

Highlights

Success Rate

86% trial completion

Treatment Research

6 treatments under study, led by Clonidine Buprenorphine

Research Leaders

15 sponsors active, led by Wilkes University

Related Conditions

Often studied with 13 related conditions

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.1%

1 terminated out of 9 trials

Success Rate

85.7%

-0.9% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 6 completed with results

Key Signals

86% success

Data Visualizations

Phase Distribution

3Total
Not Applicable (2)
Phase 2 (1)

Trial Status

Completed6
Recruiting1
Unknown1
Terminated1

Trial Success Rate

85.7%

Benchmark: 86.6%

Based on 6 completed trials

Clinical Trials (9)

Showing 9 of 9 trials
NCT05883358RecruitingPrimary

Kratom Use Disorder Management Using Clonidine and/or Buprenorphine

NCT03996096Completed

Tyrosine Kinase Inhibitor Withdrawal Syndrome in CML Patients: Observatory Trial Studying the Biological Factors.

NCT05512091Unknown

Characterization of the Pattern of Consumption and Withdrawal Syndrome From Dual Cannabis and Tobacco Use

NCT05336656Completed

Assessment of Analgesics and Sedatives in Mechanically Ventilated Patients With COVID-19

NCT04422808CompletedPrimary

AduLt iatrogEnic withdRawal sTudy in the ICU (ALERT-ICU)

NCT03645603Phase 2TerminatedPrimary

Efficacy and Safety of Dexmedetomidine During Weaning From Analgesia and Sedation in PICU (TIP-15-01)

NCT03573479Completed

Early Rehabilitation in Critically Ill Children - The PICU Liber8 Study

NCT03114904Not ApplicableCompletedPrimary

Comparison of the Efficacy of a Protocol for the Withdrawal of Neurosedation From the Usual Strategy in Cerebroses

NCT03018977Not ApplicableCompletedPrimary

Protocolized Sedative Weaning VS. Usual Care in Pediatric Critically Ill, RCT

Showing all 9 trials

Research Network

Common Treatments

  • Clonidine Buprenorphine1
  • The Sedative Weaning Protocol Group1
  • Dexmedetomidine1
  • Picu Liber8 Bundle1
  • The Usual Group1

Active Sponsors

  • Wilkes University2
  • Public Health Agency of Barcelona1
  • Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau1
  • McMaster University1
  • London Health Sciences Centre1

Top Investigators

Related Conditions

  • Iatrogenic Disease2
  • Covid191
  • Hospital Acquired Condition1
  • Cannabis Dependence1
  • Chronic Myeloid Leukemia1

Activity Timeline