Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

0.0%

0 terminated out of 23 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

9%

2 trials in Phase 3/4

Results Transparency

10%

1 of 10 completed with results

Key Signals

1 with results100% success

Data Visualizations

Phase Distribution

9Total
Not Applicable (5)
P 2 (2)
P 4 (2)

Trial Status

Completed10
Recruiting7
Unknown2
Withdrawn1
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (23)

Showing 20 of 20 trials
NCT01132885RecruitingPrimary

Defining the Brain Phenotype of Children With Williams Syndrome

NCT02706639CompletedPrimary

Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank

NCT02840448CompletedPrimary

Impact of Elastin Mediated Vascular Stiffness on End Organs

NCT07537374Not Yet RecruitingPrimary

A Case-Control Observational Study of Peripheral Blood-Derived iPSC Models to Investigate Oligodendrocyte Lineage Development in Children With Williams Syndrome and Healthy Controls

NCT07493096Recruiting

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

NCT06315699Phase 2CompletedPrimary

Clemastine Fumarate in the Treatment of Neurodevelopmental Delays in Williams Syndrome

NCT00768820Phase 4Recruiting

The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome

NCT02692846CompletedPrimary

WS-SAVE Study (Williams Syndrome Skin and Vessel Elasticity Study)

NCT06087757Phase 2Active Not RecruitingPrimary

Clemastine Treatment in Individuals With Williams Syndrome

NCT06740162Not ApplicableRecruiting

Physical Activity and Community EmPOWERment Project

NCT07285720Not ApplicableRecruitingPrimary

Phonological Constraints on Language Development in Individuals With Williams Syndrome

NCT03836300Not ApplicableEnrolling By Invitation

Parent and Infant Inter(X)Action Intervention (PIXI)

NCT01793168Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

NCT06930417Recruiting

Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants

NCT04807517Phase 4CompletedPrimary

Buspirone Treatment of Anxiety in Williams Syndrome

NCT05430763WithdrawnPrimary

Motor Deficits and Signal Conduction in Individuals With Williams Syndrome

NCT03758651CompletedPrimary

Williams Syndrome Strength, Hormones, Activity & Adiposity, DNA Programming, Eating Study

NCT04610424Not ApplicableUnknown

Cooperative Parent Mediated Therapy in Children With Fragile X Syndrome and Williams Syndrome

NCT03827525UnknownPrimary

Cognitive and Behavioral Therapy of Anxiety in Williams Syndrome

NCT02212314Not ApplicableCompletedPrimary

Response Inhibition Training for Children With Williams Syndrome

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