Transthyretin Amyloid Cardiomyopathy
19
7
10
5
Key Insights
Highlights
Success Rate
71% trial completion
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 39/100
10.5%
2 terminated out of 19 trials
71.4%
-15.1% vs benchmark
26%
5 trials in Phase 3/4
60%
3 of 5 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 5 completed trials
Clinical Trials (19)
A Study to Learn More About the Change in the Blood Levels of Transthyretin When Participants With Transthyretin Amyloidosis With Cardiomyopathy Switch From Tafamidis to Acoramidis
EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy
A Research Study to Look at the Distribution and Effects of Coramitug on Amyloid Deposits in Heart Tissue Using PET/CT Imaging in People With ATTR Amyloidosis.
Study of ALXN2220 Versus Placebo in Adults With ATTR-CM
Cardiac Amyloidosis in Patients With Aortic Stenosis
Bronx Transthyretin Amyloid Cardiomyopathy Database
A Study to Learn About the Study Medicine Called Tafamidis 61mg in People Diagnosed With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
A Study to Learn About Tafamidis in Patients With Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in India
Phenotyping and Characterization of wtATTR-CM (TRACE 1)
carDIo-ttranSSfOrm nucLEar Imaging Study
A Study to Assess the Safety and Efficacy Of Tafamidis In Chinese Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases
Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis
Early Diagnosis of Age-Linked CArdiac TransThyRetin Amyloidosis by Selective Screening in Spinal Stenosis Surgery
SGLT2 Inhibitors in Transthyretin Amyloid Cardiomyopathy
Global Prevalence of ATTR-CM in Participants With HFpEF
Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy
Artificial Intelligence to Assist the Echocardiographic Identification of Transthyretin Cardiac Amyloidosis
Clinical Comparison of Patients With Transthyretin Cardiac Amyloidosis and Patients With Heart Failure With Reduced Ejection Fraction