Key Insights

Highlights

Success Rate

73% trial completion

Published Results

24 trials with published results (62%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

15.4%

6 terminated out of 39 trials

Success Rate

72.7%

-13.8% vs benchmark

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

150%

24 of 16 completed with results

Key Signals

24 with results73% success

Data Visualizations

Phase Distribution

39Total
Early P 1 (1)
P 1 (18)
P 2 (18)
P 3 (2)

Trial Status

Completed16
Active Not Recruiting15
Terminated6
Suspended1
Withdrawn1

Trial Success Rate

72.7%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (39)

Showing 20 of 20 trials
NCT01590069Phase 1Active Not Recruiting

Aerosolized Aldesleukin in Treating Patients With Lung Metastases

NCT01955460Phase 1Active Not Recruiting

Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma

NCT02339571Phase 2Active Not Recruiting

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

NCT02196181Phase 2Active Not Recruiting

Testing Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has Spread

NCT01303341Phase 1Active Not Recruiting

Riluzole and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors or Melanoma

NCT01480154Phase 1Active Not Recruiting

Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer

NCT01364051Phase 1Active Not Recruiting

Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies

NCT00937937Phase 2Active Not Recruiting

Dinaciclib in Treating Patients With Stage IV Melanoma

NCT03276832Early Phase 1Completed

Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma

NCT01274338Phase 3Active Not Recruiting

Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery

NCT03021460Phase 1Active Not Recruiting

Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

NCT02910700Phase 2Active Not Recruiting

Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma

NCT01950390Phase 2Completed

Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

NCT01708941Phase 2Active Not Recruiting

Ipilimumab With or Without High-Dose Recombinant Interferon Alfa-2b in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

NCT01134614Phase 2Active Not Recruiting

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

NCT02965716Phase 2Active Not Recruiting

Talimogene Laherparepvec and Pembrolizumab in Treating Patients With Stage III-IV Melanoma

NCT02581930Phase 2Active Not Recruiting

Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma

NCT03384836Phase 1Suspended

Propranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by Surgery

NCT03325101Phase 1Terminated

Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma

NCT01638533Phase 1Completed

Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction

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