Key Insights

Highlights

Success Rate

38% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

12.2%

5 terminated out of 41 trials

Success Rate

37.5%

-49.1% vs benchmark

Late-Stage Pipeline

10%

4 trials in Phase 3/4

Results Transparency

267%

8 of 3 completed with results

Key Signals

8 with results38% success

Data Visualizations

Phase Distribution

39Total
P 1 (16)
P 2 (19)
P 3 (3)
P 4 (1)

Trial Status

Recruiting17
Active Not Recruiting9
Terminated5
Completed3
Not Yet Recruiting3
Suspended2

Trial Success Rate

37.5%

Benchmark: 86.6%

Based on 3 completed trials

Clinical Trials (41)

Showing 20 of 20 trials
NCT06049576Phase 1Suspended

Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma

NCT06265285Phase 2Recruiting

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

NCT03595124Phase 2Active Not Recruiting

A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

NCT07218692Phase 2Withdrawn

RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy

NCT03793166Phase 3Active Not Recruiting

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

NCT04981509Phase 2Recruiting

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

NCT05327686Phase 2Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

NCT07576725Phase 2Not Yet Recruiting

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

NCT05012371Phase 2Active Not Recruiting

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

NCT07516366Phase 2Recruiting

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial

NCT02496208Phase 1Active Not Recruiting

Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT03274258Phase 2Terminated

Phase II Trial of Nivolumab Plus Ipilimumab in Patients With Renal Medullary Carcinoma

NCT05361720Phase 2Recruiting

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

NCT03587662Phase 2Completed

Ixazomib, Gemcitabine, and Doxorubicin in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

NCT07716735Phase 1Not Yet Recruiting

Mercaptopurine for the Treatment of Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC), Uterine/Cutaneous Leiomyomas, and Kidney Cancer

NCT07226544Phase 2Recruiting

Ivonescimab Prior to Surgery for the Treatment of High-Risk Localized Clear Cell Renal Cell Cancer

NCT03284385Phase 2Active Not Recruiting

Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2

NCT06866262Phase 1Recruiting

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

NCT06942104Phase 1Recruiting

Imaging of Solid Tumors Using 18F-TRX

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