Key Insights

Highlights

Success Rate

29% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

13.2%

5 terminated out of 38 trials

Success Rate

28.6%

-57.9% vs benchmark

Late-Stage Pipeline

8%

3 trials in Phase 3/4

Results Transparency

300%

6 of 2 completed with results

Key Signals

6 with results29% success

Data Visualizations

Phase Distribution

36Total
P 1 (15)
P 2 (18)
P 3 (2)
P 4 (1)

Trial Status

Recruiting13
Active Not Recruiting11
Not Yet Recruiting6
Terminated5
Completed2
Withdrawn1

Trial Success Rate

28.6%

Benchmark: 86.5%

Based on 2 completed trials

Clinical Trials (38)

Showing 20 of 20 trials
NCT07576725Phase 2Not Yet Recruiting

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

NCT04022343Phase 2Active Not Recruiting

Neoadjuvant Cabozantinib in Treating Patients With Locally Advanced Kidney Cancer

NCT07405086Phase 4Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

NCT05327686Phase 2Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

NCT07037004Phase 2Not Yet Recruiting

Adding a Live Biotherapeutic Product (CBM588) to Pembrolizumab for the Treatment of Renal Cell Cancer After Surgery

NCT03793166Phase 3Active Not Recruiting

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

NCT04902040Phase 1Terminated

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

NCT05361720Phase 2Recruiting

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

NCT03284385Phase 2Active Not Recruiting

Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2

NCT04981509Phase 2Recruiting

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

NCT04393350Phase 2Active Not Recruiting

Perioperative Lenvatinib With Pembrolizumab in Patients With Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinoma

NCT06049576Phase 1Active Not Recruiting

Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma

NCT07516366Phase 2Not Yet Recruiting

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial

NCT02496208Phase 1Active Not Recruiting

Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors

NCT04514484Phase 1Active Not Recruiting

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT06349642Recruiting

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

NCT05012371Phase 2Active Not Recruiting

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

NCT05122546Phase 1Active Not Recruiting

CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer

NCT07128680Phase 1Recruiting

Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

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