Key Insights

Highlights

Success Rate

71% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

6.9%

4 terminated out of 58 trials

Success Rate

71.4%

-15.1% vs benchmark

Late-Stage Pipeline

7%

4 trials in Phase 3/4

Results Transparency

70%

7 of 10 completed with results

Key Signals

7 with results71% success

Data Visualizations

Phase Distribution

51Total
Not Applicable (4)
Early P 1 (2)
P 1 (25)
P 2 (16)
P 3 (4)

Trial Status

Recruiting26
Completed10
Not Yet Recruiting8
Terminated4
Active Not Recruiting3
Unknown3

Trial Success Rate

71.4%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (58)

Showing 20 of 20 trials
NCT07476287Phase 2Recruiting

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

NCT03460977Phase 1Recruiting

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

NCT07713732Phase 1Not Yet RecruitingPrimary

TLN-499 in Combination With Venetoclax in Patients With Relapsed/Refractory Solid Tumors

NCT07339059Phase 2RecruitingPrimary

Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

NCT07728955Phase 3Not Yet RecruitingPrimary

A Single-arm, Exploratory Clinical Study Evaluating the Efficacy and Safety of Bevacizumab in Combination With Anlotinib and Etoposide as First-line Therapy for Elderly Patients With Small-cell Lung Cancer or Those Who Are Intolerant to Intensive Chemotherapy

NCT07226999Phase 2RecruitingPrimary

Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer

NCT07472517Phase 3RecruitingPrimary

DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy

NCT05652686Phase 1RecruitingPrimary

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

NCT07358676Phase 2RecruitingPrimary

A Study of Bemotuzumab Plus Chemotherapy and Anlotinib Induction Followed by Bemotuzumab, Anlotinib and Consolidative Thoracic Radiotherapy in Extensive-Stage Small Cell Lung Cancer

NCT07677787Not ApplicableRecruiting

DLL3-Targeted PET/CT in Small Cell Lung Cancer

NCT07149363Phase 2RecruitingPrimary

Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer

NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT07488923Phase 1Not Yet RecruitingPrimary

A First-in-human (FIH), Phase 1 Study of ML261, an Autologous Potency Enhanced Anti-DLL3 CAR T Cell Therapy, in Participants With R/R SCLC or Select NECs (SPECTRAL-1)

NCT07508852Phase 1Recruiting

68Ga-PFD3 PET Imaging for the Diagnosis and Evaluation of Small Cell Lung Cancer

NCT07153055Phase 1RecruitingPrimary

Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer

NCT07646106Phase 1RecruitingPrimary

THE-0504 in Patients With Solid Tumors

NCT07517198Phase 1Recruiting

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

NCT07559019Phase 1RecruitingPrimary

Safety and Preliminary Activity of BI115 in Advanced SCLC

NCT07278479Phase 1Recruiting

Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors

NCT06885424Enrolling By Invitation

A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products

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