Key Insights

Highlights

Success Rate

90% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

4.8%

1 terminated out of 21 trials

Success Rate

90.0%

+3.4% vs benchmark

Late-Stage Pipeline

38%

8 trials in Phase 3/4

Results Transparency

22%

2 of 9 completed with results

Key Signals

2 with results90% success

Data Visualizations

Phase Distribution

20Total
Not Applicable (1)
Early P 1 (2)
P 1 (1)
P 2 (8)
P 3 (6)
P 4 (2)

Trial Status

Completed9
Recruiting4
Active Not Recruiting3
Unknown2
Not Yet Recruiting1
Enrolling By Invitation1

Trial Success Rate

90.0%

Benchmark: 86.6%

Based on 9 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT05797610Phase 3Active Not RecruitingPrimary

A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

NCT07750249Early Phase 1Enrolling By InvitationPrimary

The MIMIGA Study is a Randomized, Double-blind, Placebo-controlled Crossover Trial Evaluating the Safety and Efficacy of SCFA vs. Placebo. Administered Orally Once Daily With Standard Care, it Aims to Prevent CKD Progression in Biopsy-proven IgA Nephropathy by Modulating the Gut Microbiome.

NCT04557462Phase 3Active Not RecruitingPrimary

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

NCT06137768Phase 2CompletedPrimary

A Trial of HRS-5965 Tablets in Primary IgA Nephropathy

NCT07582133Phase 2RecruitingPrimary

A Trial to Evaluate the Long-term Safety and Tolerability of HRS-5965 in Patients With Primary IgA Nephropathy

NCT07354932Phase 2RecruitingPrimary

A Study of SHR-2173 in Participants With Primary IgA Nephropathy

NCT07498673Early Phase 1RecruitingPrimary

A Study of YKST02 in Participants With Primary IgA Nephropathy

NCT05799287Phase 3Active Not RecruitingPrimary

A Study of Telitacicept for IgA Nephropathy (TELIGAN)

NCT07014826Phase 3RecruitingPrimary

A Trial of HRS-5965 Capsule in Primary IgA Nephropathy

NCT06982040Phase 2Not Yet RecruitingPrimary

Evaluate the Efficacy and Safety of NTQ5082 Capsules in Patients With Primary IgA Nephropathy

NCT05847920Phase 2TerminatedPrimary

Efficacy and Safety of SHR-2010 Injection in the Treatment of Primary IgA Nephropathy

NCT04541043Phase 3CompletedPrimary

Efficacy and Safety in Patients With Primary IgA Nephropathy Who Have Completed Study Nef-301 (Nefigard-OLE)

NCT04014335Phase 2CompletedPrimary

A Study to Evaluate the Effectiveness and Safety of IONIS-FB-LRx, an Antisense Inhibitor of Complement Factor B, in Adult Participants With Primary IgA Nephropathy

NCT03643965Phase 3CompletedPrimary

Efficacy and Safety of Nefecon in Patients With Primary IgA (Immunoglobulin A) Nephropathy

NCT04291781Phase 2CompletedPrimary

A Study of RC18 Administered Subcutaneously to Subjects With Primary IgA(Immunoglobulin A) Nephropathy

NCT06589752CompletedPrimary

Replication of the NefIgArd Trial of TRF-budesonide in Primary IgAN

NCT04887532Phase 1CompletedPrimary

A Trial of HR19042 Capsule in Healthy Chinese Subjects

NCT02765594Phase 4UnknownPrimary

Hydroxychloroquine Sulfate Alleviates Persistent Proteinuria in IgA Nephropathy

NCT02712697Not ApplicableUnknownPrimary

Integrative Medicine of IgA Nephropathy

NCT02351752Phase 4CompletedPrimary

Hydroxychloroquine Sulfate for Reduction of Proteinuria in Patients With IgA Nephropathy: a Self- Controlled Study

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