Key Insights

Highlights

Success Rate

60% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 65/100

Termination Rate

22.2%

6 terminated out of 27 trials

Success Rate

60.0%

-26.5% vs benchmark

Late-Stage Pipeline

22%

6 trials in Phase 3/4

Results Transparency

67%

6 of 9 completed with results

Key Signals

6 with results60% success

Data Visualizations

Phase Distribution

20Total
Not Applicable (4)
Early P 1 (1)
P 1 (2)
P 2 (7)
P 3 (5)
P 4 (1)

Trial Status

Completed9
Terminated6
Unknown5
Recruiting4
Not Yet Recruiting2
Active Not Recruiting1

Trial Success Rate

60.0%

Benchmark: 86.5%

Based on 9 completed trials

Clinical Trials (27)

Showing 20 of 20 trials
NCT06454357Phase 2RecruitingPrimary

A Clinical Study of B007 in the Treatment of Pemphigus.

NCT05898308Phase 4RecruitingPrimary

Comparison of a Personalized Maintenance Therapy With the Standard Treatment in Pemphigus

NCT05954416Recruiting

FARD (RaDiCo Cohort) (RaDiCo-FARD)

NCT02237313Not ApplicableCompletedPrimary

Identification of Vulnerability Factors in the Course of Pemphigus Patients

NCT06696716Phase 3RecruitingPrimary

ONO-4059 Study in Patients With Steroid-resistant Pemphigus

NCT04400994Phase 2Active Not RecruitingPrimary

IVIG With Rituximab vs Rituximab as First Line Treatment of Pemphigus

NCT06904040Not ApplicableNot Yet RecruitingPrimary

A Single-center Study of CM313 in Patients With Pemphigus

NCT06654817CompletedPrimary

Efficacy and Safety Evaluation of Anti-CD20 Monoclonal Antibody Combined with Azathioprine and Corticosteroids in the Treatment of Pemphigus Vulgaris

NCT06285435Not Yet RecruitingPrimary

Coagulation Activation in Patients With Pemphigus

NCT03762265Phase 3TerminatedPrimary

A Study of PRN1008 in Patients With Pemphigus

NCT05534776UnknownPrimary

Validation of 5-Point Investigator Global Assessments for Pemphigus

NCT05284929UnknownPrimary

Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population

NCT03075904Phase 1TerminatedPrimary

A Safety and Dose-Finding Study of SYNT001 in Subjects With Pemphigus (Vulgaris or Foliaceus)

NCT01559155Terminated

Role of Proteasomes in a Dermatological Autoimmune Disease: Bullous Pemphigoid

NCT00283712Phase 2CompletedPrimary

Use of Infliximab for the Treatment of Pemphigus Vulgaris

NCT02613910Phase 3TerminatedPrimary

Long-Term Extension Study of Ofatumumab in Subjects With Pemphigus Vulgaris

NCT01313923Early Phase 1TerminatedPrimary

Evaluating Sirolimus to Treat Autoimmune Blistering Dermatosis Pemphigus

NCT00656656Phase 2CompletedPrimary

Immunoadsorption, Dexamethasone Pulse Therapy and Rituximab for Pemphigus

NCT02365675Not ApplicableUnknownPrimary

Wound Dressings for Pemphigus and Pemphigoid

NCT01974518Phase 3UnknownPrimary

Comparative Study of Rituximab Versus Combination of Rituximab and Intravenous Cyclophosphamide in Severe Pemphigus

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