Patent Foramen Ovale
76
11
16
25
Key Insights
Highlights
Success Rate
81% trial completion
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 52/100
7.9%
6 terminated out of 76 trials
80.6%
-5.9% vs benchmark
11%
8 trials in Phase 3/4
24%
6 of 25 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 25 completed trials
Clinical Trials (76)
Hummingbird ICE Study
Comparison of the Effect of Medication Therapy in Alleviating Migraine With Patent Foramen Ovale
Medical Treatment With or Without Transcatheter Patent Foramen Ovale Closure
Comparing Two PFO Closure Devices in Adults With Previous Stroke or TIA
Discontinuation of Antithrombotic Treatment Following Patent Foramen Ovale Closure in Young Patients With Cryptogenic Stroke
PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years
AMPLATZER PFO Occluder Post Approval Study
Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study
Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion
CeraFlex PFO Closure System PMCF Study
Effects of PFO Closure on Glymphatic Function and Clinical Symptoms in Patients With Migraine
Internal Microstructure of Patent Foramen Ovale Related to Stroke
Comparison of Lower vs Upper Extremity Injection Agitated Saline to Identify Patent Foramen Ovale With Echocardiography
Pioneering Advancements in Cardiocerebrovascular Interactions in the Asia pacFIC - Patent Foramen Ovale Study
Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale
Close Obstructive Sleep Apnea (OSA) Trial
Russian Registry of Endovascular Closure of PFO
Philips Intracardiac Echocardiography (ICE) Clinical Registry
GORE® CARDIOFORM Septal Occluder Migraine Clinical Study
Encore PFO Closure Device - The PerFOrm Trial