NCT07843524

Brief Summary

We will structure the study's summary to provide a clear and accessible overview for patients, families, and healthcare providers. The research will examine young adult cigarette smokers aged 18 to 24 to estimate the prevalence of a dysfunctional breathing-compatible symptom pattern using the Nijmegen Questionnaire. Furthermore, the study will assess how nicotine dependence severity-measured via the Fagerström Test for Nicotine Dependence-and physical activity levels-assessed using the International Physical Activity Questionnaire-relate to this symptom burden. We will recruit participants through social media announcements and conduct face-to-face evaluations at Istinye University. The project will employ hierarchical linear and binary logistic regression models, adjusting for age, sex, and body mass index, to determine independent predictors of dysfunctional breathing. Ultimately, the findings will provide valuable insights into the combined impacts of smoking severity and physical activity on respiratory health in young adults.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
420

participants targeted

Target at P75+ for all trials

Timeline
2mo left

Started Sep 2026

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress10%
Sep 2026Nov 2026

First Submitted

Initial submission to the registry

September 21, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 28, 2026

Completed
2 days until next milestone

Study Start

First participant enrolled

September 30, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 15, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 15, 2026

Last Updated

September 28, 2026

Status Verified

September 1, 2026

Enrollment Period

2 months

First QC Date

September 21, 2026

Last Update Submit

September 21, 2026

Conditions

Keywords

nicotine dependenceDysfunctional breathingphysical activity

Outcome Measures

Primary Outcomes (3)

  • Fagerström Test for Nicotine Dependence

    his instrument will assess the severity of nicotine dependence through six items evaluating daily cigarette consumption and smoking patterns.

    Measured once during the single face-to-face evaluation session

  • Nijmegen Questionnaire

    This questionnaire will assess the symptom burden of respiratory, neurovegetative, and neuromuscular features to identify a dysfunctional breathing-compatible symptom pattern.

    Measured once during the single face-to-face evaluation session.

  • International Physical Activity Questionnaire Short Form

    This tool will evaluate the participant's physical activity levels over the previous week by recording the duration and frequency of walking and physical activities.

    Measured once during the single face-to-face evaluation session.

Study Arms (1)

Young adult cigarette smokers.

Other: Observational evaluation.

Interventions

This study will not involve any experimental medical treatment or intervention. It will be an observational evaluation where participants will complete self-report instruments, including the Fagerström Test for Nicotine Dependence, the International Physical Activity Questionnaire, and the Nijmegen Questionnaire, along with a sociodemographic form during a single face-to-face session.

Young adult cigarette smokers.

Eligibility Criteria

Age18 Years - 24 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

The study population will consist of young adult cigarette smokers aged 18 to 24 recruited through social media announcements, who will undergo face-to-face evaluation and eligibility assessments at a single center.

You may qualify if:

  • Being between 18 and 24 years of age.
  • Reporting current cigarette smoking (daily or occasionally) at the time of assessment

You may not qualify if:

  • Having a diagnosed personality disorder.
  • Having a substance use disorder.
  • Engaging in regular meditation or breathing exercises.
  • Having a chronic cardiovascular or pulmonary disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Motor ActivityTobacco Use Disorder

Condition Hierarchy (Ancestors)

BehaviorSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Assistant Professor

Study Record Dates

First Submitted

September 21, 2026

First Posted

September 28, 2026

Study Start

September 30, 2026

Primary Completion (Estimated)

November 15, 2026

Study Completion (Estimated)

November 15, 2026

Last Updated

September 28, 2026

Record last verified: 2026-09