Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 17/100

Termination Rate

6.7%

2 terminated out of 30 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

40%

12 trials in Phase 3/4

Results Transparency

67%

4 of 6 completed with results

Key Signals

4 with results75% success

Data Visualizations

Phase Distribution

23Total
Not Applicable (2)
P 1 (6)
P 2 (3)
P 3 (10)
P 4 (2)

Trial Status

Active Not Recruiting8
Not Yet Recruiting6
Recruiting6
Completed6
Terminated2
Enrolling By Invitation1

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (30)

Showing 20 of 20 trials
NCT04657289Phase 3Active Not RecruitingPrimary

A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

NCT05904691Phase 1Active Not RecruitingPrimary

Safety and Tolerability of OCU-10-C-110 for Injection in Subjects With Neovascular Age-related Macular Degeneration

NCT06795048Phase 4Active Not RecruitingPrimary

A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration

NCT06075147Active Not Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

NCT07482176Phase 3RecruitingPrimary

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

NCT07064759Phase 3RecruitingPrimary

Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

NCT06817343Phase 1Active Not RecruitingPrimary

A Long-term Follow up Study of EXG102-031 in Patients With wAMD (Everest LTFU)

NCT06890026CompletedPrimary

Durability of Three Monthly Loading Doses With Faricimab in Treatment-naïve Neovascular Age-related Macular Degeneration

NCT07489586Phase 3Not Yet RecruitingPrimary

A Clinical Study of QL1207H Injection Versus Aflibercept for Neovascular Age-related Macular Degeneration

NCT07481500Not ApplicableNot Yet RecruitingPrimary

Speculum-Free Intravitreal Injection Using Cotton-Tipped Applicator Retraction: A Randomized Trial of Pain, Procedure Time, Patient Satisfaction, and Safety

NCT06929143Active Not RecruitingPrimary

A Study to Learn More About the Use of Aflibercept in Routine Medical Practice in Japanese Participants With Neovascular Age-related Macular Degeneration and Diabetic Macular Edema

NCT07317934Phase 3RecruitingPrimary

Efficacy and Safety of LX102 Gene Therapy in Patients With Neovascular Age-related Macular Degeneration (nAMD) (STELLAR)

NCT04514653Phase 2Active Not RecruitingPrimary

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD)

NCT07406438Phase 1Not Yet RecruitingPrimary

To Evaluate the Safety, Pharmacokinetics, and Efficacy of GB10 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)

NCT05769153Phase 1RecruitingPrimary

Study of AR-14034 in Participants With Neovascular Age-Related Macular Degeneration (nAMD)

NCT04543331CompletedPrimary

Observational Study to Evaluate Fluid Resolution and Effectiveness in Patients Receiving Beovu in Neovascular Age-related Macular Degeneration and Visual Impairment Due to Diabetic Macular Edema

NCT06856577Phase 3RecruitingPrimary

Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration

NCT06116890Phase 2Active Not RecruitingPrimary

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration

NCT05210803Enrolling By InvitationPrimary

Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMD

NCT05989126Phase 3Completed

Study to Evaluate an 8 mg Aflibercept (EYLEA®) Prefilled Syringe (PFS)

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