Narcolepsy
104
16
16
71
Key Insights
Highlights
Success Rate
96% trial completion (above average)
Published Results
27 trials with published results (26%)
Research Maturity
71 completed trials (68% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
2.9%
3 terminated out of 104 trials
95.9%
+9.4% vs benchmark
25%
26 trials in Phase 3/4
38%
27 of 71 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 71 completed trials
Clinical Trials (104)
A Phase 3 Study to Evaluate the Efficacy and Safety of Samelisant in Patients With Narcolepsy (AWAKE)
A Study to Investigate the Effect of XYWAV on Sleepiness, Polysomnography, and Functional Outcomes in Participants With Idiopathic Hypersomnia or Narcolepsy
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
A Study Evaluating the Efficacy and Safety of Xywav Expanded Dosing vs Placebo in Participants With Narcolepsy or IH
Hypersomnia in the Paediatric Population
A Trial to Test the Safety and Tolerability of Lu AH69593 in Adults That Are Healthy or Have Narcolepsy
Decreasing Nightmares in Adults With Narcolepsy
Spectrometry (MRM) Versus I 125 Radioimmunoassay (RIA) for Quantification of Orexin-A of Patients With Hypersomnolence
Narcolepsy Nightmare Study
Clinical Outcomes in Narcolepsy and Cataplexy: An Evaluation of Reboxetine Treatment (CONCERT)
WAKIX® (Pitolisant) Pregnancy Registry
Cardiovascular and Cognitive Implications of Central Disorders of Hypersomnolence and Their Treatments
Study of Psychological, Sociological and Professional Factors Associated With Maintenance of Wakefulness Test
Evaluation of Social Cognition in Patient With Type 1 or Type 2 Narcolepsy Versus Patients With Idiopathic Hypersomnia
A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy
Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies
A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy
A Switch Study From High-Sodium Oxybate to Xywav to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)
Proteomics and Metabolomics of Body Fluid in Patients With Narcolepsy