Key Insights

Highlights

Success Rate

63% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.3%

9 terminated out of 73 trials

Success Rate

62.5%

-24.0% vs benchmark

Late-Stage Pipeline

4%

3 trials in Phase 3/4

Results Transparency

60%

9 of 15 completed with results

Key Signals

9 with results63% success

Data Visualizations

Phase Distribution

52Total
Not Applicable (9)
Early P 1 (1)
P 1 (17)
P 2 (22)
P 3 (1)
P 4 (2)

Trial Status

Recruiting19
Completed15
Unknown14
Terminated9
Not Yet Recruiting8
Active Not Recruiting5

Trial Success Rate

62.5%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (73)

Showing 20 of 20 trials
NCT03192397Phase 1Active Not Recruiting

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

NCT07136077Phase 2RecruitingPrimary

A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

NCT07247201Phase 1Not Yet Recruiting

Integrating Allogeneic NK Cells in High-risk Advanced Stage III-IV Nasopharyngeal Cancer Patients

NCT03494569Phase 1Suspended

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

NCT07291921Recruiting

To Conduct Multi-omics Integrated Studies in Peripheral Blood, Such as Fragment Omics, Metabolomics and Epigenetics, and Establish Non-invasive Dynamic Follow-up Monitoring Programs During Perioperative and Postoperative Periods (Observational Study)

NCT03516279Phase 2Active Not Recruiting

Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease

NCT07413146Not ApplicableNot Yet RecruitingPrimary

Neoadjuvant CAPEOX Versus Upfront Surgery for Locally Advanced Colon Cancer With Elevated CEA: A Single-Center, Open-Label, Randomized Controlled Trial

NCT05987696Phase 1Completed

Natural Killer(NK) Cell Therapy in Acute Myeloid Leukemia

NCT05429320Phase 2Completed

A Study of Local Ablative Therapy (LAT) in People With Non-Small Cell Lung Cancer (NSCLC)

NCT01499394Recruiting

Caris Biorepository Research Protocol

NCT07350824Not ApplicableNot Yet Recruiting

Predictive Value of Minimal Residual Disease for Postoperative Recurrence and Adjuvant PD-1 Inhibitor in HCC

NCT06358430Phase 1Recruiting

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

NCT03233854Phase 1Active Not Recruiting

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies

NCT03326921Phase 1Recruiting

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

NCT02458014Phase 2Completed

Blinatumomab in Treating Patients With B-cell Acute Lymphoblastic Leukemia With Minimal Residual Disease

NCT02159495Phase 1Active Not Recruiting

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

NCT04853017Phase 1CompletedPrimary

A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors

NCT05735717Phase 2Recruiting

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

NCT06287814Recruiting

French Assessment of MRD by Liquid Biopsies in Stage III CRC Patients (FRENCH.MRD.CRC)

NCT06287749Recruiting

French Assessment of MRD by Liquid Biopsies in PDAC Patients (FRENCH.MRD.PDAC)

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