Key Insights

Highlights

Success Rate

69% trial completion

Published Results

44 trials with published results (23%)

Research Maturity

79 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

18.5%

35 terminated out of 189 trials

Success Rate

69.3%

-17.3% vs benchmark

Late-Stage Pipeline

13%

24 trials in Phase 3/4

Results Transparency

56%

44 of 79 completed with results

Key Signals

44 with results69% success35 terminated

Data Visualizations

Phase Distribution

162Total
Not Applicable (18)
Early P 1 (1)
P 1 (43)
P 2 (76)
P 3 (18)
P 4 (6)

Trial Status

Completed79
Terminated35
Recruiting24
Active Not Recruiting20
Unknown17
Withdrawn10

Trial Success Rate

69.3%

Benchmark: 86.6%

Based on 79 completed trials

Clinical Trials (189)

Showing 20 of 20 trials
NCT05155033Phase 2Recruiting

Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

NCT03595124Phase 2Active Not RecruitingPrimary

A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

NCT07218692Phase 2Withdrawn

RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy

NCT03647878Active Not Recruiting

Study of Cabozantinib as Monotherapy or in Combination With Nivolumab in Patients With Advanced or Metastatic Renal Cell Carcinoma Under Real-life Clinical Setting in 1st Line Treatment.

NCT06863311Phase 2Recruiting

Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

NCT07827482CompletedPrimary

Pretreatment 18F-FDG PET/CT Radiomics for Predicting Response to First-Line Targeted Therapy Plus Immunotherapy in Metastatic Renal Cell Carcinoma

NCT05327686Phase 2RecruitingPrimary

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

NCT07227415Phase 1Recruiting

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

NCT04467021Not ApplicableActive Not Recruiting

Cancer and Blood Pressure Management, CARISMA Study

NCT05863351Phase 3Active Not RecruitingPrimary

Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited Metastasis, SOAR Study

NCT06500455Phase 3Active Not Recruiting

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

NCT04140526Phase 1Active Not Recruiting

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

NCT03055013Phase 3Active Not RecruitingPrimary

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

NCT04090710Phase 2CompletedPrimary

SBRT With Combination Ipilimumab/Nivolumab for Metastatic Kidney Cancer

NCT05269381Phase 1Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

NCT07123090Phase 2RecruitingPrimary

A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma

NCT04788095Not ApplicableActive Not RecruitingPrimary

App-Based Mindfulness Intervention for the Improvement of Quality of Life in Patients With Metastatic Renal Cell Cancer

NCT06284564Phase 2Active Not RecruitingPrimary

A Phase II Study Bolstering Outcomes by Optimizing Immunotherapy Strategies With Evolocumab and Nivolumab in Patients With Metastatic Renal Cell Carcinoma (BOOST-RCC)

NCT03587662Phase 2Completed

Ixazomib, Gemcitabine, and Doxorubicin in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

NCT07716735Phase 1Not Yet Recruiting

Mercaptopurine for the Treatment of Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC), Uterine/Cutaneous Leiomyomas, and Kidney Cancer

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