Key Insights

Highlights

Success Rate

69% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 64/100

Termination Rate

24.4%

11 terminated out of 45 trials

Success Rate

69.4%

-17.1% vs benchmark

Late-Stage Pipeline

11%

5 trials in Phase 3/4

Results Transparency

40%

10 of 25 completed with results

Key Signals

10 with results69% success11 terminated

Data Visualizations

Phase Distribution

38Total
Not Applicable (1)
P 1 (22)
P 2 (10)
P 3 (3)
P 4 (2)

Trial Status

Completed25
Terminated11
Recruiting4
Active Not Recruiting2
Unknown1
Not Yet Recruiting1

Trial Success Rate

69.4%

Benchmark: 86.5%

Based on 25 completed trials

Clinical Trials (45)

Showing 20 of 20 trials
NCT07025512Phase 2SuspendedPrimary

177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia

NCT06517719RecruitingPrimary

Real-world Experience With Lutetium Vipivotide Tetraxetan in Metastatic Castration Resistant Prostate Cancer

NCT04104893Phase 2Active Not RecruitingPrimary

A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation

NCT07093801RecruitingPrimary

Observational Study on Lutetium (177Lu) Vipivotide Tetraxetan to Treat Metastatic Castration Resistant Prostate Cancer

NCT04729114Phase 1Recruiting

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

NCT06830850Phase 1RecruitingPrimary

A Trial of HRS-5041-103 to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of HRS-5041 in Subjects With Metastatic Castration-resistant Prostate Cancer

NCT05219500Phase 2Active Not RecruitingPrimary

Targeted Alpha Therapy With 225Actinium-Prostate Specific Membrane Antigen (PSMA)-I&T of Castration-resISTant Prostate Cancer (TATCIST).

NCT05369000Phase 1TerminatedPrimary

Trial of LAVA-1207 in Patients With Therapy Refractory Metastatic Castration Resistant Prostate Cancer (mCRPC) Resistant Prostate Cancer

NCT02975934Phase 3CompletedPrimary

A Study of Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

NCT03570619Phase 2CompletedPrimary

Immunotherapy in Patients With Metastatic Cancers and CDK12 Mutations

NCT02288247Phase 3CompletedPrimary

A Study to Assess the Benefit of Treatment Beyond Progression With Enzalutamide in Men Who Are Starting Treatment With Docetaxel After Worsening of Their Prostate Cancer When Taking Enzalutamide Alone

NCT03641560Phase 4CompletedPrimary

A Safety and Efficacy Study of Enzalutamide in Indian Patients With Progressive Metastatic Castration-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel-Based Chemotherapy

NCT06866795Phase 1Not Yet RecruitingPrimary

Phase 1 Clinical Study of GT-220F in Subjects With Metastatic Castration Resistant Prostate Cancer (mCRPC)

NCT05241613Phase 1TerminatedPrimary

A Study of AC176 for the Treatment of Metastatic Castration Resistant Prostate Cancer

NCT04869488Phase 2CompletedPrimary

A Trial of SHR3162 Combined With Apatinib Mesylate Tablets or SHR3162 Monotherapy in Patients With Metastatic Castration Resistant Prostate Cancer

NCT03454750Phase 2CompletedPrimary

Radiometabolic Therapy (RMT) With 177Lu PSMA 617 in Advanced Castration Resistant Prostate Cancer (CRPC)

NCT03328364CompletedPrimary

A Registry Based Study Evaluating Overall Survival and Treatment Length in mCRPC Patients Treated With Enzalutamide in Sweden

NCT03776968Phase 1CompletedPrimary

A Study Evaluating HC-1119 Single-Dose Pharmacokinetics and Effect of Food on Its Pharmacokinetics

NCT02495974CompletedPrimary

European Observational Study of Enzalutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)

NCT03177187Phase 1TerminatedPrimary

Combination Study of AZD5069 and Enzalutamide.

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