Key Insights

Highlights

Success Rate

89% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

6.0%

3 terminated out of 50 trials

Success Rate

89.3%

+2.8% vs benchmark

Late-Stage Pipeline

28%

14 trials in Phase 3/4

Results Transparency

32%

8 of 25 completed with results

Key Signals

8 with results89% success

Data Visualizations

Phase Distribution

38Total
Not Applicable (15)
Early P 1 (1)
P 1 (3)
P 2 (5)
P 3 (9)
P 4 (5)

Trial Status

Completed25
Unknown9
Recruiting7
Terminated3
Active Not Recruiting3
Not Yet Recruiting2

Trial Success Rate

89.3%

Benchmark: 86.5%

Based on 25 completed trials

Clinical Trials (50)

Showing 20 of 20 trials
NCT04984226Phase 2Recruiting

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

NCT07464431Phase 4Not Yet Recruiting

Sodium Bicarbonate for Critically Ill Patients With Metabolic Acidosis and Acute Kidney Injury

NCT07424625Phase 4Not Yet RecruitingPrimary

A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical Patients

NCT07355062Phase 3Recruiting

A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis

NCT05113641Not ApplicableActive Not Recruiting

Reducing Dietary Acid With Food Versus Oral Alkali in People With Chronic Kidney Disease (ReDACKD)

NCT06881641RecruitingPrimary

A Study on Bedside Formate Assay as a Diagnostic Tool in Methanol Poisoning

NCT05697770Phase 3Active Not RecruitingPrimary

SODium BICarbonate for Metabolic Acidosis in the ICU

NCT06366230Phase 1Recruiting

Adding Urea to the Final Dialysis Fluid

NCT06237712Not ApplicableActive Not RecruitingPrimary

Explorative Study to Investigate the Acid-base Response to Sodium and Potassium Salts in Patients With Chronic Kidney Disease.

NCT05005793Phase 4RecruitingPrimary

Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients

NCT06932042Not ApplicableRecruiting

PLADO for Conservative Management of CKD

NCT06908408Completed

Correlation Between Base Excess in Patients Upon Admission to the ICU and Platelet Count Trend in the Following Days

NCT04600323Early Phase 1CompletedPrimary

Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD

NCT06545565Phase 3RecruitingPrimary

Prevention of Metabolic Acidosis in Preterm Neonates by Replacing Sodium Chloride With Sodium Acetate in Parenteral Nutrition

NCT04010630Not ApplicableCompletedPrimary

Sodium Bicarbonate for the Treatment of Severe Metabolic Acidosis With Moderate or Severe Acute Kidney Injury in ICU

NCT02476253Phase 3CompletedPrimary

Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill

NCT02800343CompletedPrimary

Intraoperative Cell Salvage and Postoperative Acidosis

NCT06327737CompletedPrimary

Diabetic Ketoacidosis Diagnosis and Management

NCT05970094Not ApplicableCompleted

Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5

NCT05940935CompletedPrimary

The Relationship of Developing Metabolic Acidosis With Antiepleptic Drugs in Craniotomy Operations

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Research Network

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