Key Insights

Highlights

Success Rate

92% trial completion (above average)

Research Maturity

56 completed trials (47% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

4.2%

5 terminated out of 119 trials

Success Rate

91.8%

+5.3% vs benchmark

Late-Stage Pipeline

20%

24 trials in Phase 3/4

Results Transparency

9%

5 of 56 completed with results

Key Signals

5 with results92% success

Data Visualizations

Phase Distribution

113Total
Not Applicable (62)
Early P 1 (4)
P 1 (9)
P 2 (14)
P 3 (6)
P 4 (18)

Trial Status

Completed56
Unknown28
Not Yet Recruiting13
Recruiting8
Terminated5
Active Not Recruiting3

Trial Success Rate

91.8%

Benchmark: 86.5%

Based on 56 completed trials

Clinical Trials (119)

Showing 20 of 20 trials
NCT07540702Not ApplicableRecruitingPrimary

Injectable Platelet-Rich Fibrin Versus Intradermal Tranexamic Acid for Melasma

NCT07530016Not ApplicableNot Yet RecruitingPrimary

Clinical Efficacy and Mechanisms of a Topical Azone-Tranexamic Acid-Aloe Polysaccharide Gel in the Treatment of Melasma

NCT07522788Phase 4Not Yet RecruitingPrimary

Comparison Between Efficacy of Topical Tranexamic Acid Vs Topical Ethyl Ascorbic Acid In Treatment Of Melasma

NCT07495748Not ApplicableNot Yet RecruitingPrimary

Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma

NCT03877445Not ApplicableCompletedPrimary

Study of the Influence of Blue Light Emitted by Computer / Television Screens on Melasma MELABLUE Study

NCT07485777Not ApplicableNot Yet Recruiting

Comparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With Melasma

NCT07448415Phase 2Not Yet RecruitingPrimary

Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma

NCT07429786Not ApplicableNot Yet Recruiting

Evaluation of Efficacy and Tolerabilty of MelaB3 Serum in Combination of 35% Glycolic Acid Peeling Compared to 35% Glycolic Acid Peeling Alone in Various Hyperpigmentation Conditions

NCT06616311Not ApplicableCompletedPrimary

Efficacy of Radiofrequency Micro Needling for the Treatment of Melasma in Skin of Color.

NCT06677931Not ApplicableCompletedPrimary

Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Melasma

NCT07345507Not ApplicableCompletedPrimary

Comparison of Efficacy of Metformin Gel 30% vs Triple Combination Cream (Hydroquinone 4%, Flucinolone Acetonide 0.01%, Tretinoin 0.025%) in Treatment of Melasma in Tertiary Care Hospital Karachi

NCT07327983Not ApplicableCompletedPrimary

Azelaic Acid 20% vs Hydroquinone 4% in Epidermal Melasma

NCT07296549Enrolling By InvitationPrimary

Expert Consensus on the Clinical Management of Melasma: A Delphi Method Study

NCT07280234Early Phase 1CompletedPrimary

Comparison of Intradermal Microinjections of Tanexamic Acid and Oral Tranexamic Acid in the Management of Melasma.

NCT06644157Not ApplicableActive Not RecruitingPrimary

Treatment and Prevention of Melasma Relapses by Using 1064nm 650 Microsecond Laser

NCT07137130Not ApplicableNot Yet RecruitingPrimary

Secretome TGF Beta 3

NCT07121439Not ApplicableNot Yet RecruitingPrimary

Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES

NCT07062120Not ApplicableCompletedPrimary

Efficacy and Safety of 30% Salicylic Acid and 10% Nicotinamide Combined Therapy in Melasma

NCT07060157Not ApplicableNot Yet RecruitingPrimary

Comparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face Study

NCT06221787Not ApplicableRecruitingPrimary

Stem Cell Derived Exosomes in the Treatment of Melasma and Its Percutaneous Penetration

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