Melasma
126
9
14
59
Key Insights
Highlights
Success Rate
92% trial completion (above average)
Research Maturity
59 completed trials (47% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
4.0%
5 terminated out of 126 trials
92.2%
+5.6% vs benchmark
21%
26 trials in Phase 3/4
8%
5 of 59 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 59 completed trials
Clinical Trials (126)
Oral Tranexamic Acid Plus Triple Combination vs Triple Combination Alone in Melasma
Efficacy and Safety of a Combined Topical Formula Versus Placebo in Patients With Melasma
A Clinical Study to Evaluate the Efficacy in Improving Dark Spots After 8 Weeks of Use of Facial Sunscreens in Adult Participants
Efficacy of New Trio Combination for Melasma
Microfocused Ultrasound for Facial Pigmentary Diseases and Rosacea
A 4-week Study Investigating Two Targeted Brightening Serum (A and B) Versus 4% Hydroquinone in Women With Mild to Severe Full-face Hyperpigmentation
Comparative Efficacy of Intralesional Tranexamic Acid Versus Mandelic Acid Peel in the Treatment of Melasma
Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser
Injectable Platelet-Rich Fibrin Versus Intradermal Tranexamic Acid for Melasma
Clinical Efficacy and Mechanisms of a Topical Azone-Tranexamic Acid-Aloe Polysaccharide Gel in the Treatment of Melasma
Comparison Between Efficacy of Topical Tranexamic Acid Vs Topical Ethyl Ascorbic Acid In Treatment Of Melasma
Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma
Study of the Influence of Blue Light Emitted by Computer / Television Screens on Melasma MELABLUE Study
Comparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With Melasma
Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma
Evaluation of Efficacy and Tolerabilty of MelaB3 Serum in Combination of 35% Glycolic Acid Peeling Compared to 35% Glycolic Acid Peeling Alone in Various Hyperpigmentation Conditions
Efficacy of Radiofrequency Micro Needling for the Treatment of Melasma in Skin of Color.
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Melasma
Comparison of Efficacy of Metformin Gel 30% vs Triple Combination Cream (Hydroquinone 4%, Flucinolone Acetonide 0.01%, Tretinoin 0.025%) in Treatment of Melasma in Tertiary Care Hospital Karachi
Azelaic Acid 20% vs Hydroquinone 4% in Epidermal Melasma