Key Insights

Highlights

Success Rate

95% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

2.7%

1 terminated out of 37 trials

Success Rate

95.5%

+8.9% vs benchmark

Late-Stage Pipeline

8%

3 trials in Phase 3/4

Results Transparency

48%

10 of 21 completed with results

Key Signals

10 with results95% success

Data Visualizations

Phase Distribution

24Total
Not Applicable (3)
Early P 1 (1)
P 1 (8)
P 2 (9)
P 3 (2)
P 4 (1)

Trial Status

Completed21
Recruiting7
Unknown4
Active Not Recruiting3
Enrolling By Invitation1
Terminated1

Trial Success Rate

95.5%

Benchmark: 86.5%

Based on 21 completed trials

Clinical Trials (37)

Showing 20 of 20 trials
NCT01799538Phase 1RecruitingPrimary

Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis

NCT01552434Phase 1Active Not Recruiting

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

NCT00001465Recruiting

Study of the Disease Process of Lymphangioleiomyomatosis

NCT03304678Phase 2CompletedPrimary

Discovery of Sirolimus Sensitive Biomarkers in Blood

NCT06160310Recruiting

Tuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry)

NCT06889168Phase 1Recruiting

Evaluating the Long-term Safety and Tolerability of Imatinib in Patients With Lymphangioleiomyomatosis (LAM)

NCT05467397Phase 1Active Not RecruitingPrimary

Feasibility of [11C]Acetate-PET in LAM and TSC

NCT05676099Recruiting

TSC Biosample Repository and Natural History Database

NCT01484236RecruitingPrimary

National Lymphangioleiomyomatosis Registry, France

NCT02432560RecruitingPrimary

Safety and Durability of Sirolimus for Treatment of LAM

NCT03150914Phase 3Active Not Recruiting

Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial

NCT05727852Enrolling By Invitation

Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases

NCT01353209Phase 2CompletedPrimary

Letrozole for Lymphangioleiomyomatosis

NCT00414648Phase 3CompletedPrimary

Efficacy and Safety of Sirolimus in LAM

NCT05323370CompletedPrimary

Lymphangioleiomyomatosis, a Study on Cathepsin K

NCT02654340Terminated

Biomarkers for Tuberous Sclerosis Complex (BioTuScCom)

NCT03253913Phase 2CompletedPrimary

Resveratrol and Sirolimus in Lymphangioleiomyomatosis Trial

NCT03062943Phase 2CompletedPrimary

A Study of Nintedanib for LymphAngioleioMyomatosis (LAM)

NCT02325505Completed

Characterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and Angiomyolipoma

NCT05190627Phase 2UnknownPrimary

Effect of Loratadine in Lymphangioleiomyomatosis

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Research Network

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