Key Insights

Highlights

Success Rate

81% trial completion

Published Results

34 trials with published results (20%)

Research Maturity

80 completed trials (47% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

11.2%

19 terminated out of 169 trials

Success Rate

80.8%

-5.7% vs benchmark

Late-Stage Pipeline

17%

29 trials in Phase 3/4

Results Transparency

43%

34 of 80 completed with results

Key Signals

34 with results81% success19 terminated

Data Visualizations

Phase Distribution

125Total
Not Applicable (32)
Early P 1 (2)
P 1 (29)
P 2 (33)
P 3 (21)
P 4 (8)

Trial Status

Completed80
Recruiting21
Terminated19
Unknown18
Active Not Recruiting14
Not Yet Recruiting9

Trial Success Rate

80.8%

Benchmark: 86.6%

Based on 80 completed trials

Clinical Trials (169)

Showing 20 of 20 trials
NCT06925542Phase 1Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

NCT07629583Phase 1RecruitingPrimary

To Evaluate the Effects of Cevostamab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis

NCT07751848Phase 3Not Yet RecruitingPrimary

A Study of Outcomes in Chinese Patients Treated With Anifrolumab Who Have Active Mod-severe Systemic Lupus Erythematosus

NCT07015983Phase 2Active Not RecruitingPrimary

A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

NCT05693571Not ApplicableActive Not RecruitingPrimary

Engagement in CHildhood-Onset Systemic Lupus

NCT07438496Phase 3RecruitingPrimary

A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

NCT07201129Phase 3Recruiting

A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment

NCT05648500Phase 3Active Not RecruitingPrimary

A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus

NCT06475742Phase 3Enrolling By InvitationPrimary

Long-term Safety and Tolerability of Cenerimod in Adults With Systemic Lupus Erythematosus

NCT05672576Phase 3Active Not RecruitingPrimary

A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus

NCT07330245RecruitingPrimary

Achievement of LLDAS5 in Patients With Systemic Lupus Erythematosus Treated With Anifrolumab.

NCT07393399Not ApplicableNot Yet RecruitingPrimary

Omega-3 Supplementation in Systemic Lupus Erythematosus

NCT07381465Phase 4Active Not RecruitingPrimary

Efficacy and Safety of IL-1 Inhibitors in Mild to Moderate Systemic Lupus Erythematosus

NCT06897930Phase 1RecruitingPrimary

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

NCT02822989Not ApplicableCompletedPrimary

Using the Cholinergic Anti-Inflammatory Pathway to Treat Systemic Lupus Musculoskeletal Pain

NCT07424261RecruitingPrimary

NIS to Examine Disease Activity in SLE Patients Treated With Subcutaneous Anifrolumab in Routine Care

NCT07659704Phase 1Not Yet RecruitingPrimary

CD19-Directed CAR-T Cell Therapy in Refractory Systemic Lupus Erythematosus

NCT05141201Active Not RecruitingPrimary

SAPHNELO Systemic Lupus Erythematosus Japan Post-Marketing Surveillance (PMS)

NCT06673043Active Not RecruitingPrimary

Anifrolumab Real-world Treatment Outcomes in Systemic Lupus Erythematosus

NCT03543839Phase 4RecruitingPrimary

Trial of Belimumab in Early Lupus

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