Key Insights

Highlights

Success Rate

90% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

5.6%

4 terminated out of 71 trials

Success Rate

90.5%

+3.9% vs benchmark

Late-Stage Pipeline

35%

25 trials in Phase 3/4

Results Transparency

21%

8 of 38 completed with results

Key Signals

8 with results90% success

Data Visualizations

Phase Distribution

61Total
Not Applicable (25)
Early P 1 (3)
P 1 (1)
P 2 (7)
P 3 (5)
P 4 (20)

Trial Status

Completed38
Unknown13
Recruiting11
Not Yet Recruiting4
Terminated4
Active Not Recruiting1

Trial Success Rate

90.5%

Benchmark: 86.6%

Based on 38 completed trials

Clinical Trials (71)

Showing 20 of 20 trials
NCT06462196Recruiting

Natural History of Depression, Bipolar Disorder and Suicide Risk

NCT07838909Not ApplicableCompletedPrimary

Intraoperative Ketamine Versus Lidocaine Infusion on Postoperative Cognitive Dysfunction in Patients Undergoing Hip Surgery

NCT07680140Phase 4Recruiting

Biomarker-Guided Antidepressant Selection

NCT03362073Phase 2TerminatedPrimary

Continuous IntraVenous Infusion of Ketamine in Terminally Ill Cancer Patients

NCT07120477Phase 4Recruiting

Esketamine Versus Crisis Response Planning Versus Enhanced Treatment as Usual for Suicide Prevention: A Pragmatic Randomized Trial in a Brazilian Municipality (SAVE)

NCT07648771Not Yet Recruiting

Outcomes Registry After Ketamine Infusions for Chronic Pain: A Longitudinal Evaluation

NCT06511908Phase 2Recruiting

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

NCT07377981Phase 4Not Yet Recruiting

Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial

NCT03231683Phase 2CompletedPrimary

Use of S+Ketamine During Target-Controlled Intravenous Anaesthesia After Abdominal Hysterectomy

NCT07248202Not ApplicableCompleted

Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass

NCT07708740Not ApplicableRecruitingPrimary

Two Intravenous Doses of Ketamine in Reducing the Oculocardiac Reflex in Adult Patients Undergoing Ophthalmic Surgery

NCT06752759Phase 3Recruiting

Nebulized Ketamine for the Treatment of Major Depressive Disorder

NCT05615948Phase 4Completed

Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression

NCT07135154Completed

Postoperative Opioid Consumption in Gastric Sleeve Surgery

NCT07222007Recruiting

Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients

NCT07490457Not ApplicableNot Yet Recruiting

Intraoperative Ketamine for Chronic Postoperative Pain After Open-Heart Surgery

NCT07001605Not ApplicableCompleted

Erector Spinae Block Vs Ketamine-based Multimodal Analgesia Protocol in Lumber Decompressive Surgery

NCT07059429Not ApplicableCompleted

Ketamine Administration for Postoperative Pain Management in Patients Undergoing Knee Arthroplasty

NCT07138781Not ApplicableCompletedPrimary

Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain

NCT06431178Not ApplicableCompleted

General Anesthesia Versus Sedation By Dexmedetomidine and Ketamine With Local Infiltration for Percutaneous Transcatheter Closure of Atrial Septal Defect in Pediatric Patients

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