Key Insights

Highlights

Success Rate

91% trial completion (above average)

Published Results

17 trials with published results (37%)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

6.5%

3 terminated out of 46 trials

Success Rate

90.6%

+4.1% vs benchmark

Late-Stage Pipeline

11%

5 trials in Phase 3/4

Results Transparency

59%

17 of 29 completed with results

Key Signals

17 with results91% success

Data Visualizations

Phase Distribution

43Total
Not Applicable (6)
P 1 (16)
P 2 (16)
P 3 (4)
P 4 (1)

Trial Status

Completed29
Recruiting8
Active Not Recruiting3
Terminated3
Unknown2
Withdrawn1

Trial Success Rate

90.6%

Benchmark: 86.5%

Based on 29 completed trials

Clinical Trials (46)

Showing 20 of 20 trials
NCT04726241Phase 1Recruiting

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

NCT00662090Recruiting

Study for Epidemiology and Characterization of Myelodysplastic Syndromes (MDS) and Juvenile Myelomonocytic Leucemia (JMML) in Childhood

NCT01384513Phase 2Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

NCT03190915Phase 2Active Not RecruitingPrimary

Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

NCT03810196Not ApplicableRecruiting

CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT

NCT04024761Phase 1Recruiting

A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

NCT03326921Phase 1RecruitingPrimary

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

NCT03843528Phase 1Active Not Recruiting

Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation

NCT05735717Phase 2Recruiting

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

NCT03314974Phase 2Recruiting

Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

NCT05800210Phase 2Recruiting

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

NCT00167219Phase 1CompletedPrimary

Stem Cell Transplant for Juvenile Myelomonocytic Leukemia (JMML)

NCT05515029Phase 3Active Not Recruiting

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibitor at Patients With Hemoblastosis

NCT02338479Unknown

Natural History and Biology of Long-Term Late Effects Following Hematopoietic Cell Transplant for Childhood Hematologic Malignancies

NCT00450450Phase 3Completed

Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases

NCT01020539Phase 1Completed

Allogeneic Stem Cell Transplantation Followed By Targeted Immune Therapy In Average Risk Leukemia

NCT04082286Phase 1Completed

Yttrium-90 Anti CD66 Monoclonal Antibody in Childhood Relapsed/Refractory Leukaemia

NCT00489203Phase 2Completed

Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

NCT01445080Phase 1Completed

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

NCT02458235Phase 2Completed

Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantation

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