Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

0.0%

0 terminated out of 39 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

21%

8 trials in Phase 3/4

Results Transparency

31%

5 of 16 completed with results

Key Signals

5 with results100% success

Data Visualizations

Phase Distribution

33Total
Not Applicable (8)
P 1 (3)
P 2 (14)
P 3 (5)
P 4 (3)

Trial Status

Completed16
Recruiting15
Unknown3
Not Yet Recruiting3
Active Not Recruiting1
Enrolling By Invitation1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (39)

Showing 20 of 20 trials
NCT06752668Phase 2Recruiting

A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

NCT07096674Phase 2Recruiting

A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

NCT07500090Phase 3RecruitingPrimary

A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

NCT06812078Phase 2RecruitingPrimary

A Study of TAK-360 in Adults With Idiopathic Hypersomnia

NCT06251063Not ApplicableCompleted

Improving Social Relationships for Adolescents With Central Disorders of Hypersomnolence

NCT06767683Phase 2Recruiting

A Long-Term Study of ALKS 2680 in Subjects With Narcolepsy and Idiopathic Hypersomnia

NCT06525077Phase 3Active Not RecruitingPrimary

Safety and Efficacy of FT218 in Idiopathic Hypersomnia (REVITALYZ)

NCT06843590Phase 2RecruitingPrimary

A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Idiopathic Hypersomnia

NCT05458128Phase 3CompletedPrimary

A Long-Term Safety and Effectiveness Study to Evaluate Pitolisant in Adult Patients With Idiopathic Hypersomnia

NCT07006233Not ApplicableRecruitingPrimary

A Novel Approach to Manage Symptoms of Narcolepsy and Idiopathic Hypersomnia

NCT06252571Phase 2RecruitingPrimary

a Chronobiological Treatment Combining Evening Melatonin and Morning Light Therapy in Idiopathic Hypersomnia: a Prospective, Double Bind, Randomized, Placebo-controlled -Trial

NCT07077278Phase 4Not Yet RecruitingPrimary

Effect of Low Sodium Oxybate (LXB) on Autonomic Symptom Burden in Idiopathic Hypersomnia Patients With Postural Tachycardia Syndrome

NCT05875974Phase 4CompletedPrimary

A Study to Investigate the Effect of XYWAV on Sleepiness, Polysomnography, and Functional Outcomes in Participants With Idiopathic Hypersomnia or Narcolepsy

NCT04026958Phase 2Completed

Clarithromycin Mechanisms in Hypersomnia Syndromes

NCT05837091Phase 4RecruitingPrimary

Low Sodium Oxybate in Patients With Idiopathic Hypersomnia

NCT05371483Enrolling By Invitation

Cardiovascular and Cognitive Implications of Central Disorders of Hypersomnolence and Their Treatments

NCT01793168Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

NCT06644573Phase 1Not Yet Recruiting

Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia

NCT05668754Phase 2CompletedPrimary

Placebo-Controlled, Double-Blind, Study to Determine the Safety and Efficacy of SDX in Patients With IH

NCT06457945Not ApplicableRecruiting

Mind-wandering and Predictive Processes in Narcolepsy: a Putative Mechanism Through Covert REM Intrusions

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