Key Insights

Highlights

Success Rate

94% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

3.7%

1 terminated out of 27 trials

Success Rate

93.8%

+7.2% vs benchmark

Late-Stage Pipeline

7%

2 trials in Phase 3/4

Results Transparency

27%

4 of 15 completed with results

Key Signals

4 with results94% success

Data Visualizations

Phase Distribution

20Total
Not Applicable (7)
Early P 1 (1)
P 1 (8)
P 2 (2)
P 3 (2)

Trial Status

Completed15
Unknown4
Withdrawn3
Recruiting3
Terminated1
Enrolling By Invitation1

Trial Success Rate

93.8%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (27)

Showing 20 of 20 trials
NCT07521384Enrolling By Invitation

Real World Outcomes of Intranasal MuSE Exosomes and Stem Cells in Neurological Regenerative Therapy

NCT07493096Recruiting

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

NCT01732146Phase 3CompletedPrimary

Efficacy of Erythropoietin to Improve Survival and Neurological Outcome in Hypoxic Ischemic Encephalopathy

NCT02621944Early Phase 1RecruitingPrimary

Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia

NCT06762795Not ApplicableRecruiting

The HIEnome Study: Genome Sequencing for Perinatal HIE

NCT01471015Phase 1CompletedPrimary

Darbe Administration in Newborns Undergoing Cooling for Encephalopathy

NCT01765218Phase 1TerminatedPrimary

Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy

NCT02551003Phase 1WithdrawnPrimary

Neuroprotective Effect of Autologous Cord Blood Combined With Therapeutic Hypothermia Following Neonatal Encephalopathy

NCT06145256UnknownPrimary

Radiological Evaluation of Hypoxic Ischemic Encephalopathy

NCT05581927Not ApplicableWithdrawnPrimary

Whole-Body Hypothermia for Neonates With Hypoxic-Ischemic Encephalopathy(HIE)

NCT01481207CompletedPrimary

Magnetic Resonance Imaging and Spectroscopy Biomarkers of Neonatal Hypoxic Ischemic Encephalopathy

NCT03071783Not ApplicableCompletedPrimary

Intra-operative Feed Back on Traction Force During Vacuum Extraction: Safe Vacuum Extraction Alliance

NCT00620711Phase 1CompletedPrimary

Pilot Study of Head Cooling in Preterm Infants With Hypoxic Ischemic Encephalopathy

NCT02349672CompletedPrimary

Clinical Utility of Serum Biomarkers for the Management of Neonatal Hypoxic Ischemic Encephalopathy (Control Levels)

NCT02683915CompletedPrimary

Reno-protective Effect of Brain Cooling in Newborn With Hypoxia

NCT02287077Not ApplicableCompletedPrimary

Umbilical Cord Milking for Neonates With Hypoxic Ischemic Encephalopathy

NCT01649648Phase 1CompletedPrimary

Autologous Cord Blood Cells for Brain Injury in Term Newborns

NCT02826941Phase 2Completed

Moderate Hypothermia in Neonatal Hypoxic Ischemic Encephalopathy

NCT02578823Not ApplicableUnknownPrimary

Targeted Temperature Management After In-Hospital Cardiac Arrest

NCT01128673WithdrawnPrimary

MRI Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy(HIE)

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Research Network

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