Radiological Evaluation of Hypoxic Ischemic Encephalopathy

NCT06145256 | Unknown

• 1 other identifier: Radiological Evaluation of HIE
• Study Type: observational
• Target: 48
• Locations: 0 countries
• Sites: N/A

Brief Summary

To compare between Transcranial Ultrasound , MRI and CT in patients with Hypoxic Ischemic Encephalopathyas regards diagnostic accuracy and prognostic value .

Conditions

Hypoxic Ischemic Encephalopathy

Outcome Measures

Primary Outcomes (1)

• To determine how many children born with clinical suspicion of HIE actually have radiological findings corresponding to the clinical picture

  To determine how many children born with clinical suspicion of HIE ( low apgar score , low pH in blood gases within first hours of delivery, disturbed level of consciousness and neonatal seizures ) actually have radiological findings corresponding with the clinical picture

  one year

Interventions

MRI brain, MSCT brain, Transcranial Ultrasound DEVICE

MRI, MSCT and transcranial Ultrasound are an important diagnostic modalities in the assessment of severity and outcome of HIE

Eligibility Criteria

• Age: 1 Hour - 28 Days
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

* study population comprised of all term and preterm newborns who suffered perinatal asphyxia and all neonatal with clinical manifestations suggestive of hypoxic ischemic encephalopathy : 1. disturbed level of consciousness 2. low apgar score 3\_ low pH in blood gases within the first hours of delivery 4\_ neonatal seizures within first 48 h of delivery and excluded Those newborns with : <!-- --> 1. CNS infections 2. sepsis 3. respiratory distress 4. metabolic disorders 5. major congenital malformations From the study

You may qualify if:

• all term and preterm newborns who suffered perinatal asphyxia and all neonatal with clinical manifestations suggestive of hypoxic ischemic encephalopathy :
• disturbed level of consciousness
• low apgar score 3\_ low pH in blood gases within the first hours of delivery 4\_ neonatal seizures within first 48 h of delivery

You may not qualify if:

• Those newborns with :
• CNS infections
• sepsis
• respiratory distress
• metabolic disorders
• major congenital malformations Were excluded from the study

Sponsors & Collaborators

• Assiut University: lead

Related Links

• Related Info

MeSH Terms

Conditions

Hypoxia-Ischemia, Brain

Condition Hierarchy (Ancestors)

Brain Ischemia; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Hypoxia, Brain; Vascular Diseases; Cardiovascular Diseases; Hypoxia; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Esraa Azab Abdelatty, Master

CONTACT

01100328593; esraaazab700@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator at Assuit University pediatric department

Study Record Dates

• First Submitted: October 18, 2023
• First Posted: November 24, 2023
• Study Start: December 10, 2023
• Primary Completion: December 31, 2024
• Study Completion: March 31, 2025
• Last Updated: December 7, 2023

Record last verified: 2023-12