Key Insights

Highlights

Success Rate

84% trial completion

Published Results

36 trials with published results (22%)

Research Maturity

107 completed trials (66% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

12.4%

20 terminated out of 161 trials

Success Rate

84.3%

-2.2% vs benchmark

Late-Stage Pipeline

28%

45 trials in Phase 3/4

Results Transparency

34%

36 of 107 completed with results

Key Signals

36 with results84% success20 terminated

Data Visualizations

Phase Distribution

123Total
Not Applicable (28)
Early P 1 (2)
P 1 (15)
P 2 (33)
P 3 (30)
P 4 (15)

Trial Status

Completed107
Terminated20
Unknown15
Withdrawn7
Recruiting5
Active Not Recruiting3

Trial Success Rate

84.3%

Benchmark: 86.5%

Based on 107 completed trials

Clinical Trials (161)

Showing 20 of 20 trials
NCT04945460Phase 2CompletedPrimary

A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16)

NCT03626688Phase 3Completed

A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

NCT04175600Phase 3Active Not RecruitingPrimary

A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension

NCT05179876Phase 3RecruitingPrimary

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option

NCT02562235Phase 3Active Not RecruitingPrimary

Riociguat in Children With Pulmonary Arterial Hypertension (PAH)

NCT06814145Phase 2RecruitingPrimary

Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)

NCT07473700Phase 2Not Yet RecruitingPrimary

Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease

NCT07079592Not ApplicableRecruiting

A Deep-Learning-Enabled Electrocardiogram for Detecting Pulmonary Hypertension

NCT03683186Phase 3Enrolling By Invitation

A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

NCT02759419Phase 4CompletedPrimary

A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension.

NCT05719415Not ApplicableRecruitingPrimary

Functional Pulmonary Capillary Surface Area in BPA for CTEPH

NCT04193046Early Phase 1CompletedPrimary

A Study for the Identification of Biomarker Signatures for Early Detection of Pulmonary Hypertension (PH)

NCT01065454Phase 2CompletedPrimary

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction

NCT00694850Phase 2CompletedPrimary

Impact of Multiple Doses of BAY63-2521 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Patients With Interstitial Lung Disease (ILD) Associated Pulmonary Hypertension (PH)

NCT07087613RecruitingPrimary

Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG

NCT04718350Not ApplicableCompletedPrimary

Treatment of Pulmonary Hypertension in High-risk Cardiac Surgery Patients Using Inhalational and Intravenous Agents

NCT04732221Phase 2Completed

A Study of the Efficacy and Safety of Frespaciguat (MK-5475) in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)

NCT03754660Phase 1CompletedPrimary

This Study Tests the Safety of Inhaled BAY1237592, How the Drug is Tolerated and How it Effects Patients With High Blood Pressure in the Arteries of the Lungs in the Two Different Disease Groups Pulmonary Arterial Hypertension (PAH) and Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

NCT04565990Phase 3CompletedPrimary

A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study

NCT04480723Early Phase 1CompletedPrimary

A Study for the Identification of Biomarker Signatures for Diagnosis of Pulmonary Hypertension (PH) in Participants at Low or Intermediate Probability of PH Undergoing Cardiac Magnetic Resonance Imaging

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