Key Insights

Highlights

Success Rate

83% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

10.5%

4 terminated out of 38 trials

Success Rate

82.6%

-3.9% vs benchmark

Late-Stage Pipeline

21%

8 trials in Phase 3/4

Results Transparency

26%

5 of 19 completed with results

Key Signals

5 with results83% success

Data Visualizations

Phase Distribution

29Total
Not Applicable (11)
Early P 1 (1)
P 1 (1)
P 2 (8)
P 3 (5)
P 4 (3)

Trial Status

Completed19
Unknown5
Recruiting4
Terminated4
Withdrawn3
Suspended2

Trial Success Rate

82.6%

Benchmark: 86.5%

Based on 19 completed trials

Clinical Trials (38)

Showing 20 of 20 trials
NCT06095440RecruitingPrimary

A Retrospective Analysis of Outcomes in Patients With Hepatorenal Syndrome at Methodist Dallas Medical Center

NCT06256432Phase 2Active Not RecruitingPrimary

Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome

NCT06525623Not ApplicableRecruiting

Initial Resuscitation for Acute Kidney Injury in Cirrhosis

NCT07460908Not ApplicableCompletedPrimary

Comparison of Terlipressin Versus Octreotide in Patients With Hepatorenal Syndrome

NCT02097784Not ApplicableCompleted

Interest of the Echocardiography in the Management of Cirrhotic Patients With Acute Kidney Injury

NCT06161766Completed

Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease

NCT04898010Not ApplicableSuspended

The Selective Cytopheretic Device (SCD) for Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS) Type I

NCT06000748Phase 2Terminated

NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients

NCT02434445RecruitingPrimary

Use of Novel Plasma and Urinary Biomarkers to Predict the Development of Hepatorenal Syndrome in Cirrhotic Patients

NCT05346393Not ApplicableRecruiting

HRS-AKI Treatment With TIPS in Patients With Cirrhosis

NCT04460560Phase 3CompletedPrimary

Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE)

NCT04048707Phase 2WithdrawnPrimary

Angiotensin 2 for Hepatorenal Syndrome

NCT05387811Completed

International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project

NCT05309200Phase 2Completed

A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury

NCT05875948Phase 2UnknownPrimary

Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome

NCT05434286UnknownPrimary

Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Hepatorenal Syndrome-Acute Kidney Injury

NCT04416282Not ApplicableCompleted

Efficacy of Early Terlipressin Plus Albumin Therapy in Comparison to Standard Treatment for HRS-AKI in Acute-on-chronic Liver Failure.

NCT02770716Phase 3CompletedPrimary

Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1

NCT01143246Phase 3CompletedPrimary

A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin

NCT03483272CompletedPrimary

MRI to Assess the Effect of Terlipressin in Patients With Acute Hepatorenal Syndrome (HRS-AKI)

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