Key Insights

Highlights

Success Rate

86% trial completion

Published Results

17 trials with published results (10%)

Research Maturity

77 completed trials (45% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

7.6%

13 terminated out of 170 trials

Success Rate

85.6%

-1.0% vs benchmark

Late-Stage Pipeline

26%

44 trials in Phase 3/4

Results Transparency

22%

17 of 77 completed with results

Key Signals

17 with results86% success13 terminated

Data Visualizations

Phase Distribution

124Total
Not Applicable (42)
Early P 1 (2)
P 1 (13)
P 2 (23)
P 3 (14)
P 4 (30)

Trial Status

Completed77
Unknown43
Recruiting17
Terminated13
Withdrawn8
Not Yet Recruiting7

Trial Success Rate

85.6%

Benchmark: 86.5%

Based on 77 completed trials

Clinical Trials (170)

Showing 20 of 20 trials
NCT07612670Not Yet RecruitingPrimary

A Prospective Cohort Study on the Epidemiological Investigation, Diagnosis, and Treatment of Hepatic Encephalopathy

NCT04862221Phase 2Recruiting

TReatment for ImmUne Mediated PathopHysiology

NCT07587671Not ApplicableNot Yet Recruiting

Underdilated VCX-TIPS Versus EVL Plus NSBB for Secondary Prophylaxis of Variceal Bleeding in Cirrhosis

NCT05425316CompletedPrimary

Speech in Hepatic Encephalopathy (HE)

NCT07553858Not ApplicableNot Yet RecruitingPrimary

Endoscopic Shunts Embolization for Refractory Hepatic Encephalopathy

NCT07528690Phase 2Not Yet RecruitingPrimary

Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)

NCT07521332Phase 4Recruiting

Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis

NCT06052176Phase 2Recruiting

Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement

NCT07480096Phase 2Completed

Efficacy and Safety of Lemborexant for Patients With Cirrhosis and Sleep Problems

NCT07454408Phase 1Not Yet RecruitingPrimary

Evaluation of the Outcome of Fecal Microbiota Transplantation

NCT07437638Active Not Recruiting

Clinical Efficacy and Survival Prediction Analysis of Transjugular Intrahepatic Portosystemic Shunt in Patients With Liver Cirrhosis

NCT07418008Recruiting

The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)

NCT06425380Not ApplicableRecruitingPrimary

Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic Encephalopathy

NCT06987968Phase 2TerminatedPrimary

A Study to See if an Investigational Medicine Called VS-01 Can Help and How Safe it is in the Treatment of Patients With Overt Hepatic Encephalopathy

NCT03420482Phase 2Active Not RecruitingPrimary

Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy

NCT04096014Not ApplicableRecruitingPrimary

Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy

NCT03267615Recruiting

VICIS - Vienna Cirrhosis Study

NCT05297448Phase 3Active Not RecruitingPrimary

Evaluation of Rifaximin SSD for Delaying Encephalopathy Decompensation in Patients With Cirrhosis

NCT05754996Phase 3CompletedPrimary

Efficacy and Safety of Nifuroxazide in the Treatment of Hepatic Encephalopathy in Egyptian Patients With Liver Cirrhosis

NCT07046429Not ApplicableRecruitingPrimary

Affect of Melatonin on Sleep and Cognition in Cirrhosis

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