Heart Failure With Reduced Ejection Fraction
222
47
61
83
Key Insights
Highlights
Success Rate
87% trial completion (above average)
Published Results
19 trials with published results (9%)
Research Maturity
83 completed trials (37% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
5.4%
12 terminated out of 222 trials
87.4%
+0.8% vs benchmark
15%
33 trials in Phase 3/4
23%
19 of 83 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 83 completed trials
Clinical Trials (222)
[11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction
Home-Based Cardiac Rehabilitation for Patients With Heart Failure
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
Intermediate Outcomes of HFrEF Patients on Guideline-Directed Medical Therapy
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Utilization of Guided Point of Care Ultrasound in Heart Failure Diagnosis Pilot Trial
Yoga Based Cardiac Rehabilitation in Heart Failure Failure
Midodrine in Heart Failure With Reduced Ejection Fraction With Hypotension
Ketones in Heart Failure With Reduced Ejection Fraction
STEPwise De-escalation and Optimizing Withdrawal of ARNI and SGLT2i in Normalized Heart Failure
A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF)
Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score
Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure
Circulating RNA Markers of Ventricular Arrhythmias in Remotely Monitored Patients With Post-Infarction Heart Failure and Implanted Cardioverter-Defibrillators
HFrEF Polypill in Sri Lanka RCT
A Study Investigating the Impact of IMT With CR On Exercise Responses In HF
Respiratory Sinus Arrhythmia (RSA) Pacing Post-CABG Surgery in Patients With HFrEF
Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure
A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure