Heart Failure With Reduced Ejection Fraction
215
45
58
77
Key Insights
Highlights
Success Rate
87% trial completion (above average)
Published Results
18 trials with published results (8%)
Research Maturity
77 completed trials (36% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
5.6%
12 terminated out of 215 trials
86.5%
+0.0% vs benchmark
15%
33 trials in Phase 3/4
23%
18 of 77 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 77 completed trials
Clinical Trials (215)
Emulation of the EMPEROR-Reduced Trial Using Healthcare Claims Data
STEPwise De-escalation and Optimizing Withdrawal of ARNI and SGLT2i in Normalized Heart Failure
HF Patients With LVADs Being Treated With SGLT2i
PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF
An Early Feasibility Study Evaluation of an Implant Free Interatrial Shunt to Improve Heart Failure
STRATegy SUccesS in High-Risk PCI With Impella CP: Evaluation of Hemodynamic Protection in Complex PCI
Assessment of Combined CCM and ICD Device in HFrEF
High Fat Diet for Cardiac Metabolic Reprogramming
Study of JK07 in Patients With Chronic Heart Failure
Dietary Intervention and Physical Activity in Patients With Heart Failure and Reduced Ejection Fraction
HFrEF Polypill in Sri Lanka RCT
Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy
ERTU-SODIUM: Study on the Effects of Ertugliflozin on Sodium Storage, Interstitial Volume, and Plasma Volume in HFrEF
Phase Ib/IIa Trial With AC01 in Patients With HFrEF
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Ketones in Heart Failure With Reduced Ejection Fraction
Pilot Study Lp299v Supplementation in Chronic Heart Failure
Midodrine in Heart Failure With Reduced Ejection Fraction With Hypotension
Lokelma for RAAS Maximisation in CKD & Heart Failure.
Digital Remote Management Versus Usual Care for Optimization of Guideline-directed Medical Therapy in Patients With Heart Failure and Reduced Ejection Fraction: a Multicentre, Randomised, Controlled Trial (DigiCare-HFrEF)