Key Insights

Highlights

Success Rate

76% trial completion

Published Results

152 trials with published results (17%)

Research Maturity

353 completed trials (40% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.4%

110 terminated out of 889 trials

Success Rate

76.2%

-10.3% vs benchmark

Late-Stage Pipeline

6%

50 trials in Phase 3/4

Results Transparency

43%

152 of 353 completed with results

Key Signals

152 with results76% success110 terminated

Data Visualizations

Phase Distribution

763Total
Not Applicable (135)
Early P 1 (48)
P 1 (293)
P 2 (237)
P 3 (45)
P 4 (5)

Trial Status

Completed353
Recruiting157
Terminated110
Active Not Recruiting92
Unknown81
Not Yet Recruiting49

Trial Success Rate

76.2%

Benchmark: 86.5%

Based on 353 completed trials

Clinical Trials (889)

Showing 20 of 20 trials
NCT02152982Phase 2Active Not RecruitingPrimary

Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT05902169Phase 3RecruitingPrimary

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

NCT03970447Phase 2RecruitingPrimary

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

NCT07285044Phase 2Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT07735819Phase 2Not Yet Recruiting

Positron Emission Tomography/Computed Tomography (PET/CT) Imaging in Patients Diagnosed With a Glioma

NCT05781321Phase 2Active Not RecruitingPrimary

Short Course Radiotherapy for the Treatment of Patients With Glioblastoma, SAGA Study

NCT04555577Phase 1Active Not RecruitingPrimary

Phase I Trial of DNA-PK Inhibitor (PEPOSERTIB ) in Combination With Radiation and Adjuvant Temozolomide in Newly Diagnosed MGMT Unmethylated and Recurrent Glioblastoma

NCT07464925Phase 1Recruiting

A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

NCT06991101Phase 2RecruitingPrimary

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

NCT03297125Active Not RecruitingPrimary

Assessment of Optune Therapy for Patients With Newly Diagnosed Glioblastoma Using Advanced MRI

NCT06161519Phase 1Recruiting

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

NCT07731555Not ApplicableRecruitingPrimary

Characterization of the Blood-Brain Barrier in High-Grade Glioma Through Immunohistochemical, Transcriptional, Fluorescein and Radiological Analyses

NCT01339052Phase 2CompletedPrimary

Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma

NCT02974738Phase 1Active Not Recruiting

A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001)

NCT06556563Phase 3RecruitingPrimary

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

NCT06973096Phase 1Active Not RecruitingPrimary

CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy

NCT06672575Phase 1RecruitingPrimary

A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma

NCT07089641Phase 1RecruitingPrimary

ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial

NCT07715097Phase 2Not Yet RecruitingPrimary

Survivin-Targeted Dendritic Cell (DC) Cell Injection for Newly Diagnosed Glioblastoma

NCT04479696Not ApplicableRecruitingPrimary

Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors

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