Glioblastoma
873
154
246
343
Key Insights
Highlights
Success Rate
76% trial completion
Published Results
148 trials with published results (17%)
Research Maturity
343 completed trials (39% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 59/100
12.4%
108 terminated out of 873 trials
76.1%
-10.5% vs benchmark
6%
50 trials in Phase 3/4
43%
148 of 343 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 343 completed trials
Clinical Trials (873)
RMC-5552 Monotherapy in Adult Subjects With Recurrent Glioblastoma
Pharmacoscopy for Patients With Refractory Primary Brain Tumors
LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)
Impact of Fluorescence-Guided Resection and Chemoradiotherapy on the Systemic Immune Response in Glioblastoma: A Kinetic Analysis of Immune Biomarkers.
Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma
Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors
Pediatric Long-Term Follow-up and Rollover Study
ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
Safety and Efficacy Study of Anti-B7-H3 CAR-T Cell Therapy for Recurrent Glioblastoma
INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)
Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations
PH Sensitive MRI Based Resections of Glioblastoma
Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma
Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)
A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma
EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma
First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma
MRinRT: Swansea University and SWWCC Collaboration Study.
Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care