Key Insights

Highlights

Success Rate

76% trial completion

Published Results

154 trials with published results (17%)

Research Maturity

356 completed trials (40% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.2%

110 terminated out of 900 trials

Success Rate

76.4%

-10.2% vs benchmark

Late-Stage Pipeline

6%

50 trials in Phase 3/4

Results Transparency

43%

154 of 356 completed with results

Key Signals

154 with results76% success110 terminated

Data Visualizations

Phase Distribution

773Total
Not Applicable (137)
Early P 1 (49)
P 1 (296)
P 2 (241)
P 3 (45)
P 4 (5)

Trial Status

Completed356
Recruiting156
Terminated110
Active Not Recruiting97
Unknown81
Not Yet Recruiting51

Trial Success Rate

76.4%

Benchmark: 86.6%

Based on 356 completed trials

Clinical Trials (900)

Showing 20 of 20 trials
NCT06964815Not ApplicableWithdrawnPrimary

Silibinin in Association With Concomitant Chemoradiotherapy and Maintenance Temozolomide in STAT3 Positive IDH Wild-type, Newly Diagnosed Glioblastoma Patients

NCT06991101Phase 2RecruitingPrimary

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

NCT02179086Phase 2Active Not RecruitingPrimary

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

NCT03970447Phase 2RecruitingPrimary

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

NCT07285044Phase 2Recruiting

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

NCT05871021Phase 2Active Not RecruitingPrimary

Protective VEGF Inhibition for Isotoxic Dose Escalation in Glioblastoma

NCT05902169Phase 3RecruitingPrimary

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

NCT07145112Phase 1RecruitingPrimary

Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma

NCT05183204Phase 2CompletedPrimary

Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma

NCT07422896Phase 1Not Yet RecruitingPrimary

A Phase I First-in-human Trial of Bvax (B-cell Vaccination) in Addition to Standard of Care Chemoradiotherapy for Newly Diagnosed Glioblastoma

NCT07195591Phase 3RecruitingPrimary

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

NCT07568782Not Yet RecruitingPrimary

Impact of Fluorescence-Guided Resection and Chemoradiotherapy on the Systemic Immune Response in Glioblastoma: A Kinetic Analysis of Immune Biomarkers.

NCT05635734Phase 1CompletedPrimary

Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma

NCT07515924Early Phase 1Not Yet RecruitingPrimary

Oral Gallium Maltolate for Recurrent Glioblastoma

NCT05353530Phase 1Active Not Recruiting

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma

NCT07821112Phase 2Not Yet Recruiting

Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Treated With Cesium-131 GammaTile®

NCT03174197Phase 1CompletedPrimary

Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

NCT03197506Phase 2Active Not RecruitingPrimary

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

NCT05109728Phase 1Active Not RecruitingPrimary

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

NCT06804655Phase 2Recruiting

Pharmacoscopy for Patients With Refractory Primary Brain Tumors

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