Key Insights

Highlights

Success Rate

86% trial completion

Published Results

14 trials with published results (18%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

10.5%

8 terminated out of 76 trials

Success Rate

86.0%

-0.5% vs benchmark

Late-Stage Pipeline

13%

10 trials in Phase 3/4

Results Transparency

29%

14 of 49 completed with results

Key Signals

14 with results86% success

Data Visualizations

Phase Distribution

66Total
Not Applicable (8)
P 1 (16)
P 2 (32)
P 3 (9)
P 4 (1)

Trial Status

Completed49
Unknown13
Terminated8
Recruiting2
Active Not Recruiting2
Withdrawn1

Trial Success Rate

86.0%

Benchmark: 86.5%

Based on 49 completed trials

Clinical Trials (76)

Showing 20 of 20 trials
NCT02834013Phase 2Active Not Recruiting

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

NCT00265798Phase 2Active Not RecruitingPrimary

Sorafenib in Treating Patients With Malignant Gastrointestinal Stromal Tumor That Progressed During or After Previous Treatment With Imatinib Mesylate and Sunitinib Malate

NCT07434843Phase 2Recruiting

PH 2 Pemigatinib in SDH-deficient GIST

NCT03493152UnknownPrimary

Expanded Access to Everolimus, for an Individual Patient With GIST (Gastrointestinal Stromal Tumors)(CTMS#18-0019)

NCT02331914CompletedPrimary

GIST: Assessment of Tumor Mutations and TKI Plasma Exposure

NCT02734823Withdrawn

Long Term Effects of Tyrosine Kinase Inhibitor Therapy on Ovarian Reserve and Fertility in Patients With Chronic Myeloid Leukemia or Gastrointestinal Stromal Tumor

NCT00764595Phase 2CompletedPrimary

Imatinib Mesylate in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor

NCT00769782Phase 2CompletedPrimary

Surgery in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor

NCT02880020Phase 2CompletedPrimary

Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery

NCT02924714Not ApplicableSuspendedPrimary

SSG XXV: The Stop-GIST Trial; Discontinuation of Imatinib in Patients With Oligo-metastatic GIST

NCT04933669Phase 2Recruiting

Prospective Multicenter Clinical Study of Neoadjuvant Imatinib Mesylate for Gastrointestinal Stromal Tumors

NCT02164240Phase 1CompletedPrimary

Phase Ib Study of SUnitinib Alternating With REgorafenib in Patients With Metastatic and/or Unresectable GIST

NCT02185937Phase 1TerminatedPrimary

Influence of an Acidic Beverage on the Imatinib Exposure After Major Gastrectomy

NCT00028002Phase 2CompletedPrimary

Neoadjuvant and Adjuvant Imatinib Mesylate in Treating Patients With Primary or Recurrent Malignant Gastrointestinal Stromal Tumor

NCT01068769Phase 2CompletedPrimary

Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor

NCT04256226CompletedPrimary

Clinical Outcome of Female Non-gastric Gastrointestinal Stromal Tumor

NCT04143048UnknownPrimary

A Study on Non-invasive Early Diagnosis of Gastrointestinal Stromal Tumors and Differentiation of Benign and Malignant Nodules

NCT02686944Phase 1CompletedPrimary

A Study to Evaluate the Safety of Intuvax Administered Intra-tumorally in Patients With Gastrointestinal Stromal Tumors

NCT00428220Not ApplicableCompleted

A Continuation Study Using Sunitinib Malate For Patients Leaving Treatment On A Previous Sunitinib Study.

NCT00568750Phase 2CompletedPrimary

Dasatinib as First-Line Therapy in Treating Patients With Gastrointestinal Stromal Tumors

Scroll to load more

Research Network

Activity Timeline