Key Insights

Highlights

Success Rate

96% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

3.3%

1 terminated out of 30 trials

Success Rate

96.0%

+9.5% vs benchmark

Late-Stage Pipeline

53%

16 trials in Phase 3/4

Results Transparency

33%

8 of 24 completed with results

Key Signals

8 with results96% success

Data Visualizations

Phase Distribution

27Total
Not Applicable (2)
P 1 (1)
P 2 (8)
P 3 (15)
P 4 (1)

Trial Status

Completed24
Recruiting4
Terminated1
Withdrawn1

Trial Success Rate

96.0%

Benchmark: 86.5%

Based on 24 completed trials

Clinical Trials (30)

Showing 20 of 20 trials
NCT05939453Not ApplicableRecruiting

Impact of Bright Light Therapy on Prader-Willi Syndrome

NCT04789174Phase 4CompletedPrimary

Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study

NCT07082829Phase 1RecruitingPrimary

A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age

NCT05458128Phase 3Completed

A Long-Term Safety and Effectiveness Study to Evaluate Pitolisant in Adult Patients With Idiopathic Hypersomnia

NCT05113745Phase 3Completed

A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)

NCT06872593Not ApplicableRecruitingPrimary

Validating a Novel Driving Simulation-based MWT Against the Standard MWT in an OSA-cohort Challenged by CPAP-withdrawal

NCT04886518Phase 2Completed

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

NCT06898008CompletedPrimary

Characterization of Children with Complaints of Excessive Daytime Sleepiness

NCT05059223Phase 3Completed

A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy

NCT03194217Phase 2CompletedPrimary

BEN-2001 in Parkinson Disease Patients With Excessive Daytime Sleepiness

NCT06103825Phase 3Completed

A Twelve-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Solriamfetol in the Treatment of Excessive Daytime Sleepiness (EDS) in Patients with Obstructive Sleep Apnea (OSA)

NCT06711159Recruiting

SLEEPINESS - a Search for a Biomarker of Excessive Daytime Sleepiness in Severe Obstructive Sleep Apnoea - An Explorative Study

NCT05822128CompletedPrimary

Alternative Epworth Sleepiness Scale ESS-ALT in French

NCT05223166Phase 3CompletedPrimary

A Clinical Study to Evaluate the Efficacy and Safety of Pitolisant in the Treatment of EDS in Patients With OSA

NCT04923594Phase 2Completed

Four-week Study of the Safety and Efficacy of NLS-2 (Mazindol Extended Release) in the Treatment of Narcolepsy

NCT02720744Phase 3CompletedPrimary

Once-Nightly Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

NCT02739568Phase 3CompletedPrimary

Pitolisant (BF2.649) in the Treatment of EDS in Patients With OSA

NCT02978651Phase 3WithdrawnPrimary

Pitolisant (BF2.649) in the Treatment of Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnoea Syndrome, Treated or Not by Nasal Continuous Positive Airway Pressure, But Still Complaining of Excessive Daytime Sleepiness

NCT01800045Phase 3Completed

Pitolisant to Assess Weekly Frequency of Cataplexy Attacks and EDS in Narcoleptic Patients (HARMONY CTP)

NCT00620659Phase 2Terminated

Treatment of Refractory Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSA/HS) Using Nasal Continuous Positive Airway Pressure (nCPAP) Therapy (0249-015)

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