Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.3%

2 terminated out of 24 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

33%

2 of 6 completed with results

Key Signals

2 with results75% success

Data Visualizations

Phase Distribution

16Total
Not Applicable (14)
P 2 (2)

Trial Status

Recruiting8
Completed6
Unknown4
Active Not Recruiting2
Terminated2
Not Yet Recruiting2

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (24)

Showing 20 of 20 trials
NCT06211439Not ApplicableCompletedPrimary

Transcranial Alternating Current Stimulation in Patients With Disorders of Consciousness

NCT07736820Not Yet RecruitingPrimary

Multimodal Assessment and Prognosis in Disorders of Consciousness After Severe Brain Injury (CyDoC-MAP)

NCT07711119Not Yet RecruitingPrimary

Cross-cultural Adaptation and Multicenter Validation of the Italian Versions of the Brief Evaluation of Receptive Aphasia (BERA) and SWallowing Assessment in Disorders of Consciousness (SWADOC)

NCT06930716Not ApplicableRecruitingPrimary

Paired Vagus Nerve Stimulation in Mobilization of Patients With Prolonged Disorders of Consciousness

NCT07277309Not ApplicableRecruitingPrimary

Promoting Recovery After Brain Injury Using Focused Ultrasound

NCT06939348Not ApplicableRecruitingPrimary

Ultrasound Stimulation for Patients in a Disorder of Consciousness

NCT06088628RecruitingPrimary

Micro-expressions in Patients With Prolonged Disorders of Consciousness

NCT06406413RecruitingPrimary

Micro-movements in Patients With Prolonged Disorders of Consciousness

NCT06568536Not ApplicableRecruitingPrimary

Measuring Brain Complexity to Detect and Predict Recovery of Consciousness in the ICU

NCT06744114Active Not RecruitingPrimary

Etiologies, Definitive Diagnosis and Patient Outcomes in Altered Level of Consciousness in the Emergency Department

NCT06389344Not ApplicableRecruiting

Effect of Esketamine on Conscious State in Patients With pDoC

NCT06443827Phase 2Active Not Recruiting

Effect of Intravenous Amantadine Sulphate on Disorders of Consciousness

NCT06426615Not ApplicableRecruiting

Connectivity and Neural Signatures of Consciousness in Unresponsive States

NCT02644265Unknown

CONNECT-ME: Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG

NCT02522429Not ApplicableTerminatedPrimary

Thalamic Low Intensity Focused Ultrasound in Brain Injury

NCT02772302Not ApplicableCompletedPrimary

Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome

NCT03367078TerminatedPrimary

tDCS in Patients With Disorder of Consciousness Due to Severe Acquired Brain Injury

NCT02667899Not ApplicableUnknownPrimary

The Consciousness Variation of Deep Brain and Transcranial Magnetic Stimulation for Disorders of Consciousness Patients

NCT03060317CompletedPrimary

Validation of the Russian Version of Coma Recovery Scale-Revised (CRS-R)

NCT02659228Not ApplicableUnknownPrimary

Assessing Covert Consciousness in Unresponsive Patients

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