Key Insights

Highlights

Success Rate

77% trial completion

Published Results

20 trials with published results (16%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

11.1%

14 terminated out of 126 trials

Success Rate

77.4%

-9.2% vs benchmark

Late-Stage Pipeline

3%

4 trials in Phase 3/4

Results Transparency

42%

20 of 48 completed with results

Key Signals

20 with results77% success14 terminated

Data Visualizations

Phase Distribution

118Total
Not Applicable (5)
Early P 1 (3)
P 1 (73)
P 2 (33)
P 3 (4)

Trial Status

Completed48
Recruiting26
Unknown18
Terminated14
Withdrawn9
Active Not Recruiting7

Trial Success Rate

77.4%

Benchmark: 86.6%

Based on 48 completed trials

Clinical Trials (126)

Showing 20 of 20 trials
NCT05442515Phase 1Recruiting

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

NCT06350318Phase 2Recruiting

Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas

NCT06820268Phase 1RecruitingPrimary

A Study of XS-04 in Patients With Relapsed or Refractory Hematologic Malignancies

NCT07101328Phase 1Recruiting

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

NCT05615636Phase 2Recruiting

A Phase II Trial of Mosunetuzumab, Polatuzumab, Tafasitamab, and Lenalidomide in Patients With Relapsed B-cell NHL

NCT04993690Phase 1RecruitingPrimary

A Study of LP-168 in Participants With Relapse or Refractory B-Cell Lymphoma

NCT07168486Phase 1Enrolling By InvitationPrimary

CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas

NCT06634589Phase 1Recruiting

A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

NCT07652580Recruiting

Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma

NCT07516093Phase 3RecruitingPrimary

Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL

NCT07520006Phase 1RecruitingPrimary

Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies

NCT04792502Phase 2Recruiting

Mosunetuzumab With Lenalidomide Augmentation as First-line Therapy for Follicular and Marginal Zone Lymphoma

NCT07775508Phase 1RecruitingPrimary

In Vivo CD19/CD20 CAR T-Cell Therapy for Relapsed/Refractory B-Cell Lymphoma

NCT05092451Phase 1RecruitingPrimary

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

NCT05365659Phase 1Recruiting

IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas

NCT05024045Phase 1Completed

Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

NCT05653271Phase 1CompletedPrimary

ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies

NCT05934838Phase 1Active Not Recruiting

A Feasibility Trial of Tazemetostat Plus CAR T Cell Therapy in B-cell Lymphomas

NCT07616089Phase 1Not Yet RecruitingPrimary

Phase I Study of FXS0683 in the Treatment of Blood Tumors

NCT07593482Phase 2Not Yet RecruitingPrimary

Bendamustine Versus Fludarabine/Cyclophosphamide for Lymphodepletion in Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T): a Randomized Trial.

Scroll to load more

Research Network

Activity Timeline