Autosomal Dominant Polycystic Kidney Disease (ADPKD)
32
5
10
16
Key Insights
Highlights
Success Rate
89% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 30/100
6.3%
2 terminated out of 32 trials
88.9%
+2.4% vs benchmark
28%
9 trials in Phase 3/4
25%
4 of 16 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 16 completed trials
Clinical Trials (32)
Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease
Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)
Polycystic Kidney Disease 1 (PKD1) Gene Variant Groups in Autosomal Dominant Polycystic Kidney Disease
RADIOLOGICAL AND CLINICAL EVALUATION OF RENAL EMBOLIZATION USING EVOH IN DIALYSIS PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE: A PROSPECTIVE LONGITUDINAL OBSERVATIONAL STUDY
Lanreotide In Polycystic Kidney Disease Study
Effects of VX-407 on the Pharmacokinetics of Oral Contraceptives in Healthy Participants
A Phase 1 Study Evaluating Safety, Tolerability, and Pharmacokinetics of VX-407 in Healthy Participants
A Possible Founding PKD2 Mutation Associated With Variable Phenotypes of ADPKD in Bergamo Province
Metabolic Impacts of Ren-Nu: A Dietary Program for Polycystic Kidney Disease
Phase 1 Study to Evaluate the Safety and Tolerability of Intravenously Administered PYC-003
Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease
Robotic vs Open Nephrectomy for ADPKD
Canadian Medical Assessment of JINARC™ Outcomes Registry
Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease
Drug-Drug Interaction of JMKX003142 With Amiodarone and Febuxostat in Healthy Subjects
Simulated and Synthetic Health Data: Improving Clinical Research on Rare Diseases. A Real-World Data Simulation of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Trials. A Retrospective, Observational Study
A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of VX-407 in Healthy Participants
Study of Tamibarotene in Patients With ADPKD
Artificial Intelligence-based Image Processing Methods to Advance the Characterization of Polycystic Kidney Disease
Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autosomal Dominant Polycystic Kidney Disease)